最新刊期
      卷 0 ， 期 0 ， 2020
      • Issue 5, (1994)
        摘要：mTc-L, L-EC renal dynamic imaging studies in 75 subjects were performed including 15 healthy volunteers and 60 patients.The study on volunteers shows that 99mTc- L,L- EC uptake and clearance in kidney is rapid,Tmax was 3.07±0.59min and 3.22±0.75min in left and right kidney respectively, more than 73%,,99mTc-L,L- EC was eliminated from kidney in 20 min. 99mTc- L, L- EC renal imaging and renography in 60 patients was correlated well with the clinical diagnosis and/or other examination. The preliminary resultS demonstrated that 99mTc-L,L-EC has a promising future in the clinical renal functional imaging.  
        关键词：Renal imaging;￣（99m）Tc- L;L- EC   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：The 3,24 h 131I and 30 min 99mTc uptake rates have been measured in 101 cases with thyroid disease. The 30 min 99mTc uptake rate was also measured in 22 cases with normal thyroid.The results showed that 30 min 99mTc uptake rate of normal thyroid were 3.73±1.56.The coincident rate of increased value in 99mTc uptake with fall uptake were 82.4%,while those of decreased and normal value were 91.3% and 88.5% respectively.Above studies have shown that in functional image of thyroid 99mTc uptake is more useful than 24h 131I uptake test.  
          
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：RIL-2 was labelled with 125I by Iodogen method.The products were punned by HPLC.Analysis of each radiolabelled preparation showed that greater than 95% of the radioiodine was associated with a single protein peak.The specific activity of radioiodinated rIL- 2 was approximately 2.2×1016-2.8×1016Bq/mol. The 125I-rIL-2 was designed for quantitating human IL-2 with sensitive radioimmunoassay （RIA）.The bioactivity of 125I- rIL- 2 is good.  
        关键词：Recombinant human interlukin 2;￣（125）I- rIL- 2;Radioimmunoassay（RIA）   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：A cerebrograph imaging system was investigated for the diagnosis of cerebrovascular diseases.This system can quantitatively analyse and map the regional cerebral blood flow（rCBF）and also the electroencephalography（EEG）.The mapping of cerebellum-brain stem area was also realized. This system is the first one to combine the technology of nuclear medicine with electrophysiology, and thereby provide a combined information about the rCBF and the function of brain with coloured rCBF mapping,topogtaphical EEG mapping and quantitative data at the same time.It has important value for the early diagnosis of brain diseases,especially for the cerebral vascular accident.  
        关键词：Cerebrograph imaging;Cerbrograph imaging system;rCBF mapping system;rCBF and EEG mapping system;Cerebrum-cerebellum-stem blood now mapping   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：SPECT images and CT scan were reported in 158 cerebral diseases, including 84 acute cerebral diseases,50 epilepsy,12 brain tumor,7 migraine, and 5 Parkinson’s diseases.The results revealed that SPECT was better than CT for the early diagnosis of ischemic stroke and transient ischemic attacks,although the CT had more advantages for the location and qualitative diagnosis of acute cerebral diseases.It was also showed that SPECT had its unique value in the diagnosis of epilePSy,but its value in the diagnosis of brain tumor and Parkinson’s disease was uncertain.  
        关键词：Brain disorders;Radionuclide imaging;Tomography   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：By paper chromatagraphy method, taking 0.9% Nacl（System Ⅰ） and 85%methanol （System Ⅱ） as two developing solvent systems, the Rf values of 99mTc,99mTc- colloid and 99mTc- MDP were determined.They are respectively 0.68-0.76,0 and 1.0 in System Ⅰ; 0.6-0.7, 0 and 0 in System Ⅱ.This result indicates 99mTc-colloid can be separated from 99mTc and 99mTc-MDP with SystemⅠ;99mTc separated from 99mTc-colloid and 99mTc-MDP with System Ⅱ. The result indicates the radiochemical purity of 99mTc-MDP can be determined by the two developingsolvent systems and developing under nitrogen pressure in SystemⅠ.The method is convenient,feasible and effective.  
        关键词：9m)Tc- MDP;Radiochemical purity;Paper chromatagraphy   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：A stable isotope dilution method was established for measuring total body water in htunans using 18O and 2H labelled water.The results indicate that the 18O multi-point tracer method is most reliable.Since 18O water is currently very expensive,it is suggested that the 2H2O multi-point or single point method may also be used if appropriate corrections can be established by careful comparison with the H218O multi-point method.  
        关键词：Total body water;￣（18）O labelled water;Carbon dioxide production rate;Stable isotope dilution method   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：levated serum acidic isoferritin（AIF）level was observed in 8 groups of cancers patients with RIA. AIF was better than ferritin for the diagnosis of tumour,the best sensitivity and specificity was obtained in hepatoma.These findings suggested that the increased AIF in the serum of patients is produced by the tumor. Therefore,serum AIF level could be used for the diagnosis of hepatoma.  
        关键词：Acidic isoferritin;Radioimmunoassay;Hepatoma;Lung cancer;Stomach carcinoma;AFP   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：Adriamycin was labelled with tritium by photosensitised induced reaction with a specific activity of 90TBq/mol.Adriamycin was conjugated to monoclonal antibody against hUman brain gliama cell using polyaldeyl dextran （PAD） as the binding agent.The conjugate was purified by sephadex G-100. The UV spectrum of the labelled product coincides the UV spectrum of the conjugate of unlabelled adriamycin and the same monoclonal antibody.A marked enrichment of the tritium labelled conjugate was found in the tyansplanted human brain glioma of nude mice.  
        关键词：?H-Adriamycin;Monoclonal antibody against human brain glioma;Tritium labelling;Photosensitized reaction   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：对一组接受９９ｍＴｃ标记抗ＣＥＡ单克隆抗体放射免疫显像的肠癌病人用反向间接血凝试验测定其血清中人抗鼠抗体（ＨＡＭＡ），结果发现７／１０血样品中有ＨＡＭＡ，其浓度随注射次数增加而增大．  
        关键词：放射免疫显像;反向间接血凝法;人抗鼠抗体;监测   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：Mouse experiment revealed that the concentration of 99mTc-EC in kidney was highly dependent on the chemical amount of the injected tracer.A highest concentration in kideney was found at a dose of 1.25 mg per kg of body weight,with a kidney/liver ration as high as 3.2.Its toxicity was low and only a small percentage was bound to plasma protein. Preliminary study on 14 healthy volunteers suggests that 99mTc- EC is a hopeful functional imaging agent for kidney.  
        关键词：?99m)Tc- EC;Renal functional imaging   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：In this paper a systematic and scientific mathematical model have been established to measure the effective renal plasma now （ERPF） using the regression and computer knowledge by the evidence of well correlated relationship between ERPF and renographic index.In comparison with the precondial body surface measuing method,several advantages has been revealed:no need of blood withdrawl,less radioactivity,less interfering factor in processing and easy to operate etc.  
        关键词：Regression meastire method;Renal function measurement;ERBF   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：study on 125I labelled tPA and its in vivo distyibution in animal tumor is reported.The result suggests that tPA can accumulate in tumor and may be a potential tumor imaging agent.  
        关键词：Tissue plasminogen activatot;Radiopharmaceutical   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：o test the better tumor/liver ratio in tumor- bearing mice,the present study was carried out in various conditions to illustrate the applicability of 99mTc （V）-DMSA imaging in hepatic tumor.Various experimental conditions were tested by different kinds of experimental tumor,concentration of the ligand, imaging time post-injection, and pH（pH8-9） etc.the positive rate of 99mTc（V）-DMSA SPECT imaging in 35 patients with hepatic carcinoma,were 88.5%.The results demonstrated that 99mTc（V）-DMSA can be used as an effective imaging agent for Hepatic Cancer.  
        关键词：Dimercaptosuccinic acid;Radionuclide imaging;Hepatic Carcinoma;Biodistribution   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：he expression of c-myc gene on 24 cases of gastrocarcinoma and 6 cases of gastric ulcer was studied by nucleic acid hybridization with 32P c-myc-cDNA and abp c-myc-DNA as probes. RNA-DNA dot showed high expression in 3/7 medullary gastrocarcinoma,1/3 mucoid agstrocarcinoma and 1/14 gastric adenocarcinoma.Molecular weight of c-myc mRNA in tumor tissue had no significant change compared with control.No multiplication and rearrangement were discovered by southern blot.  
        关键词：Gastrocarcinoma;c-myc gene;Deoxyribonucleic acid probe;Nucleic acid hybridization   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：sing Sophy DSX SPECT and 32P or 90y as the radioactive sources, the optimal bremsstrahlung imaging condition with different collimators,various widths of energy window, and different distance etc was discussed.The results showed that the bremsstrahlung spectrum was continious,the satisfactory images can be obtained with high-energy collimator and 80keV-60% energy window scale or empirical-window;when the distance between collimator and source was short.Preliminary clinical result was also satisfactory.Thereby, it was suggested that SPECT can be applied to bressmtrahlung imaging.  
        关键词：Bremsstyahlung;Radionuclide imaging;Model test   
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：提高质量办出特色面向全国──祝“医学中的核技术”专刊创办三周年蒋茂松《核技术》的“医学中的核技术”自１９９０年１１月以专刊形式刊出以来已三载多了。核医学专刊的出版是顺应了国内外迅速发展的核医学事业的需要．为广大核医学工作者又增添了一块广阔的学术园地。...  
          
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        发布时间：2021-04-09
      • Issue 5, (1994)
        摘要：atients were examined by both the ECG-gated SPECT and planar imaging.It was found that ejection fractions（EF） of left ventricular measured by ECG SPECT imaging well correlated with that measured by planar imaging（r>0.7,P<0.0001）,but EF of right ventricular has no correlation（r<0.5,P>0.05）.However,the end-diastolic and end-systolic volume between left and right ventricular has significantly different（P<0.05）.The result showed that ECG-gated SPECT imaging can overcome the overlapping between atricles and ventricles,thereby it was beneficial for the detection of the lesions over the inferior and hasal portion of left and right ventricular.  
        关键词：Heart function test;Radionuclide angiology imaging;Tomographys imaging;Multi-gated blood pool imaging   
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        发布时间：2021-04-09
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