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      卷 0 ， 期 0 ， 2020
      • Jiang Maosong Tang Xi He Wei
        Issue 11, (1993)
        摘要：Dipyridamo.le 99mTc MIBI myocadial imaging one day protocol was performed in 161 patients with CAD. The overall sensitivity for the detection of CAD was 91%. The sensitivities and specificities for detecting individual vessel involvement were 88% for LAD, 81% and 66% for RCA and 77% and 72% for Lcx, respectively. The results showed that the one day protocol provides a convenient method with the same high sensitivity as the two days protocol.  
          
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        发布时间：2021-04-09
      • Deng Shenzhen Zhang Jinming Cheng Wei Lin XiangtongZhang Qingbo Wu Xianghui
        Issue 11, (1993)
        摘要：In this paper, serum CA-50 level was measured in 63 patients with hepatitis B)HBV) by using CA-50 IRMA kit, the results are compared with 109 normal blood donors, 11 cases of hepatocellular carcinoma（HCC）. CA-50 levels of all normalpersons were less than 17U/ml （4.4 ±6.2U/ml）, but in 63 patients with HBV, CA-50 level was higher than 17U/ml in 48 cases （76%）, while CA-50 level in HCC group was higher than normal in all the cases.  
          
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        发布时间：2021-04-09
      • Gui Zhining Hu Xiaoke Lu Hanping Fan WeiWu Naiyun Gao Jinhui
        Issue 11, (1993)
        摘要：The androgen receptors in biopsy specimens of 22 cases of human prostatic cancer（PC） were studied by radioligand binding assay. The cytoplasmic androgen receptor （AcR） and nuclear androgen receptor（AnR） densities wewe 305.70±461.68 and 363.04±391.44 pmol/g protein respectively, both were significantly higher than those of 36 benigh prostatic hypertrophy （BPH） and 9 normal prostate（NP）. Among the prostatic cancers, the AnR/AcR ratios were significantly different between metastatic and primary cancers. This result suggested that there might be migration of AR from nucleus to cytosoi in the process of metastasis. The serum testosterone studied by RIA method are significantly lower than that of BPH and NP. Thawmounted autoradiography demonstrated that AR were mainly located in epithelial cells of the glandular tissue of prostate.  
          
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        发布时间：2021-04-09
      • Wu Chanqun Jiang yimin Li Yinmin
        Issue 11, (1993)
        摘要：A guantivitive radioimmunoassay of transferrin was established. Its antisera was obtained by immunizing rabbits with purified transferrin and the titer was as high as 1:6×104 with an affinity constant of 1.15×1012 l/mol. Ferrin, lactoferrin and serum aibimin showed no significant interference. The sensitivity was 2.54 ng/tube and the recovery was X =102.91%. The inter-batch CV was 1.8% （n = 14） and intra-batch CV was 9.94% （n=10）. The transferrin level （X±SD） of serum, urine and saliva in healthy adults measured by this method were 3.03±0.66 g/l （n = 31）, 198±98 μg/l （n=55） and 557.89±206.32 μg/l （n=12） respectively. Serum transferrin in iron deficiency anemia were 6.46±4.15 g/l （n= 134）. 29 out of 35 cases of patients with abnormai. renal function had their urine transferrin higher than normal.  
          
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        发布时间：2021-04-09
      • Wang Yunhui Huo Tongshu Ji Changqing Mei Nan Zhang Tao
        Issue 11, (1993)
        摘要：In this paper, the authors have reported AFP level in the blood serum of 2223 normal pregnant women in different semesters by RIA method. All the data were made by statistical analysis. The result has shown that the AFP level was normal during the first 12 weeks of pregnancy. Then, it gradually increases from the 13th week and reaches its maximum（184.6±74.6 μ g/l） at 32nd week. Later on it tends to decrease slowly, but still remains over 100 μg/l in parturient period. Therefore, it was suggested that AFP in pregnant women have substantial difference and regularity between different semesters but without any significant correlation with their ages.  
          
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        发布时间：2021-04-09
      • Deng Shouzhan Lin Xiangtong Huang Chun Zhang XuepingHe Wanting Fang Zujun Song Jianda
        Issue 11, (1993)
        摘要：The serum PSA and PAP were measured in 23 cases of prostatic carcinoma, 42 cases of benign prostatic hypertrophy and 21 cases of non-prostatic disease. Significant differences had been found between prostatic carcinoma and benign prostatic hypertrophy or control group. According to the Decision Matrix for general clinical evaluation. The diagnostic index and availability of serum PSA and PAP were 135.8%, 138.3% and 0.36, 0.40, respectively. The study showed that the measurement of the serum PSA and PAP should be complementary each other for the diagnosis and differential diagnosis of prostatic carcinoma. Finally, it was considered that the measurement of the serum PSA is superior to that of PAP for therapeutic follow- up in patients with prostatic carcinoma.  
          
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        发布时间：2021-04-09
      • Zhang Yingnan Gao Fengtong Xiao Yanling
        Issue 11, (1993)
        摘要：In 23 normal subjects, 37 CAD-NMI and 14 CAD-MI, left ventricular function was assessed using an automated method from equilibrum radionuclide ventriculography. Early diastolic function was measured for evaluting its clinical value in coronary artery diseaes. The results showed that PFR was more sensitive than the others for detecting ischaemic heart disease. There were significant difference on PFR between normal subjects and CAD-NMI group（p<0.01） and PFR values of 35 in 37 CAD- NM1 were lower than that of normal subjects. The order of sensitivity in other indices were TPFR（20/37, p<0.01） = PER（20/37, p<0.01）>PER（17/37, p<0.05） >（16/37, p>05）. There were also significant difference in PFR, PER and EF between CAD-NMI and CAD- MI （p<0.01）, while there was no difference in TPFR and TPER（p>05）.  
          
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        发布时间：2021-04-09
      • Li Shengli Liu Yongchang Lin Xiangtong Deng Shouzhen Li Ming
        Issue 11, (1993)
        摘要：Radioiodinated AMT is a new positive imaging agent for brain tumour. In this paper, its radioiodination, purification, and biodistribution in mice is described. AMT was labelled with 125I/131I using either chloramine-T or iodogen method. The labelling rate was 60% to 80%. After column chromatography on sephadex LH-20, the radiochemical purity was greater than 98%. Animal experiments showed that 25I-AMT was eliminated from blood rapidly and was mainly excreted through kidney. 5, 15, 30, 60 minutes after tail vein injection, the radioactivities of brain tissue per gram was 4.14%, 2.50%, 2.13%, 1.24% of injection dose respectively.  
          
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        发布时间：2021-04-09
      • Zhao Zhoushe Zhou Qian
        Issue 11, (1993)
        摘要：Three scatter correction techniques including （Ⅰ） single energy window,（Ⅱ） dual energy window, and （Ⅲ） multi- energy window weighted acquisition were compared in this study. Results indicated that the contrast and percentage fraction standard deviation（FSD%） were smallest in Ⅰ and largest in Ⅲ, as calculated from phantom test and clinical application. Although the result of Ⅲ is the best, its calculation is very complicated and occupies more disk space. It concludes that Ⅱ is more suitable for routine clinical use, due to its simplicity and accuracy.  
          
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        发布时间：2021-04-09
      • Lin Wei Ye Guangchun Wu Hengfu Ding Zhihui Yuan Gewen
        Issue 11, (1993)
        摘要：99mTc-DTPA renal dynamic imaging were performed in 75 patients to measure glomerular filtration rate（GFR）, among them creatinine clearance rate（Ccr） was also measured in 23 and two blood sample method was measured in 31. The result showed that GFR has a good correlation with Ccr（r= 0.8326, p< 0.0001） and two blood sample method（r=0.8436,p<0.0001）. Also use of factor analysis for image processing have further improved the image quality.  
          
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        发布时间：2021-04-09
      • Ma Qingjie Zhao Jie Xiao Yanling
        Issue 11, (1993)
        摘要：Immunoreactivity of 125I- anti-Tg- McAb（18A1 and 18A11） with cells of normal thyroid and tumor was determined by cell binding assay. Results showed that the binding percentage found in differentiated throid carcinoma medullary thyroid carcimena, benign thyroid tumor, and other cells was >30%, 8%-12%, <10% and <4% respectively. Binding percentage of 125I-McAb with differentiated thyroid carcinoma cells was significantly higher than that of normal thyroid and benign thyroid tumor. No binding with cells of malignant tumor coming from the other tissue was confirmed. Ratio of binding percentage on differentiated thyroid carcinoma with normal thyroid cells was also determined as 3.4-4.3（simple McAb）,and 5.0（"cocktail" McAb）. Therefore both 18A1 and 18A11 can be successfully used for radioimmu-noimaging of differentiated thyroid carcinoma and its metastatic sites.  
          
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        发布时间：2021-04-09
      • Luo Shineng Xie Minhao Xi Yuefen Feng Yingying Guo Yuzhi
        Issue 11, (1993)
        摘要：This paper reports the preparation and biodistribution of 99mTc-cyclo-hexanedione dioxime （99mTc-CDO） and its methaneboronic acid adduct （99mTc-CDO-MeB）. The result showed that pH value exerts greater effect on the labelling yield of 99mTc- CDO- MeB than that of 99mTc- CDO. When pH value was 3.5-4.0, the labelling yield of 99mTc-CDO-MeB was higher than 90%. Biodistribution experiment showed that 99mTc-CDO-MeB was taken by heart and brain in the first few minutes after intravenous injection. The uptakes of 99mTc-CDO-MeB by heart and brain were higher than those of 99mTc- CDO.  
          
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        发布时间：2021-04-09
      • Fang Ping Wu Chunying Luo Shineng Feng Yingying Xie MinhaoKuang Qinfang
        Issue 11, (1993)
        摘要：99mTc- MRP20[N- （2（1H- pyrrolylmethyl））N’-（4- pentene- 3- one- 2）ethane-1,2-diamine], a new brain perfusion imaging agent is reported in this paper. MRP20 was synthesized and characterized. Its chemical structure was confirmed by IR, UV, NMR, MS and element analysis. Using SnCl2 as reducing agent, MRP20 forms a stable complex with 99mTcO（Ⅲ）. The labelling yield and rediochemical purity were both higher than 90%.  
          
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        发布时间：2021-04-09
      • Zhu Jun Yao Wenjiu Ma Jixiab
        Issue 11, (1993)
        摘要：m-iodobenzylguanidine（mIBG） is radio- iodinated by nucleophilic isotopic exchenge using Cu（Ⅰ） as catalyst and in the presene of excess reducing agent. The method is simple and rapid. A 95% labelling yield can be obtained within 30 minutes at 100℃.  
          
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        发布时间：2021-04-09
      • Wang Fujun Cao Xueli Wang Yunhui
        Issue 11, (1993)
        摘要：In this paper, 20 patients with acute viral myocarditis were treated by Ginseng-Ophiopogon（Sen Mai） injection（test group） and GIK and other 20 patients were treated with vitamin C（controls）. The results showed that the plasma level of atrial natriuretic factor （ANF） was raised during treatment and the rise in the test group was earlier than the control group. The possible mechanism was discussed briefly.  
          
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        发布时间：2021-04-09
      • Zhang Qinghua Guo Wei Zhang Junping
        Issue 11, (1993)
        摘要：51Cr releasing assay has been widely used for detecting cytotoxicity. The correlation coefficient between 51Cr and traditional cyto-colony inhibition test was 0.9915（p<0.001）, thereby this method may be available for cytotoxicity detection. The advantages and disadvantages of the two methods for cytotoxicity were compared and discussed. 51Cr releasing assay was considered to be much simpler and quicker, also can be recommended to be used in clinical practice.  
          
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        发布时间：2021-04-09
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