YUEWeisheng LI Xiaolin YU Xiaohan DENG Biao LIU Jiangfeng WAN Tianmin ZHANG Guilin LI Van
Issue 11, (2004)
摘要:Synchrotron radiation micro-beam X-ray fluorescence was applied to analyze the atmospheric aerosol particles in Shanghai city. The experiment was carried out at the X-ray fluorescence station of 4W1B beam line of Beijing Synchrotron Radiation Facility (BSRF). The excitation energy was in a range of 3.5-30keV, and the beam size was 20 μm× 10 μm. We measured both pollution source samples and environmental monitor samples collected at Wusong, Shanghai city. The results show that the particles from different pollutant sources were characterized by their own X-ray spectra. Therefore the origin of environmental monitor aerosol particles can be deduced by a comparison between spectra of environmental monitor particles and those of pollution source particles.
摘要:Beamline 3B1B, a VUV beamline in Beijing Synchrotron Radiation Laboratory, was designed for the studies on VUV fluorescence spectroscopy and VUV circular dichroism spectroscopy of biological macromolecules. Due to the very small acceptance and bad vacuum, the beamline didn’t fulfill the experiments well in past years. A new VUV beamline was designed since 2001, the photon wavelength range is from 120nm to 350nm. The beamline’s construction was finished and it was put into use in March 2003. The test result shows its photon flux and resolution are greatly improved. In the paper, design and performance of the beamline is introduced.
WANG Yinsong Li Aiguo WEI Lun ZHANG Yuanxun LI Deyi QIU Huiyuan LI Yan ZHANG Guilin
Issue 11, (2004)
摘要:The study on elemental speciation in airborne particulate matter (PM) is important for its evaluation of toxicity and source of pollution. In the present work, samples of airborne PM were collected in different site and with different size, and the X-ray absorption near-edge structure (XANES) spectra of Cr, Mn, Cu and Zn were measured. The oxidation state of these elements and possible chemical speciation are discussed using the spectra The results show that in our samples, the oxidation state of Cr is likely tervalent, Mn exists mainly as divalence, Cu also exists as divalence and Zn exists mainly as sulfate. The elemental concentrations in the samples were determined by proton induced X-ray emission (PIXE), The difference in concentrations was observed for samples from different site and with different size, but obvious difference in speciation was not found.
摘要:The information of isotopes in two-layer nuclear material is included in the y spectra. Based on a kind of gamma-ray self-absorption correction, a simple analytic method is introduced. The layered structure characteristic of samples can be gotten directly using the method. Through the further data processing, the detailed information about composition has been attained. Using the two-layered mixed-uranium as the sample, we have made the numeric simulation tests and obtained some good results.
摘要:Crystalline silicon samples were implanted at room temperature with 1.55MeV 3He ions at different doses ranging from 5 × 1015 to 5 × 1016 /cm2. Damage production after subsequent high temperature annealing was studied by using cross-sectional transmission electron microscopy (XTEM). Meanwhile, nuclear reaction analysis (NRA) was used to study the behavior of 3He desorption from the implanted samples. Our results show that at low dose range, the He implantation followed by high temperature annealing only induces the creation of small dislocations, and at intermediate dose range, clusters of bubbles accompanied with high density of dislocation loops were observed, while for the higher implanted dose, a well defined cavity band was formed at the depth corresponding to the projected 3He range. The phenomena were discussed in combination with NRA results.
关键词:Crystalline silicon;MeV level He implantation;Bubble clusters;Cavities;XTEM
摘要:The taproot, leteral root and the growth of hypocotyl and root/shoot ratio of plant seedlings are important characteristics relevant to seedling drought tolerance. The N+ ion beams with 25keV energy and the doses of 600-3600 × 2.6 × 1013 · cm-2 were implanted into the liquorice dry seeds, among which 1800 × 2.6 × 1013 · cm-2 could improve effectively the taproot growth of liquorice seedlings at period of 6d and root/shoot ratio (dry weight and fresh weight) and promote the development of lateral roots of liquorice seedlings at the period of 30d, and stimulate obviously the growth of hypocotyl and taproot and stem height of seedlings at the period of 6d and 30d. The parameters can be considered as those of energy and dose of N+ ion beam irradiation whose M1 mutagenesis effect on liquorice plant vegetation in desert area is to be studied for reference. Within the implantation parameter ranges in this experiment,the response of N+ implantation to drought tolerant characteristics of liquorice seedlings also shows the "damage-repair-damage" effect.
摘要:To prepare magnetic nanoparticles and to explore its application in radioimmunoassay (RIA) , aqueous decanoic acid-coated Fe3O4 magnetic nanoparticles were synthesized by chemical coprecipitation with Fe2+ and Fe3+ ions included in microemulsions with ammonia water. The sheep anti-rabbit IgG was immobilized into the magnetic nanoparticles by physical adsorption. The complex of the magnetic nanoparticles and the sheep anti-rabbit IgG (magnetic nanoparticle second antibody) was then used as magnetic separation carrier for RIA. The magnetic nanoparticle size, size distributions, polydispersity etc were determined by photon correlation spectroscopy (PCS) and transmission electron microscopy (TEM). Some influence factors such as of buffer pH used for immobilizing sheep anti-rabbit IgG, amount of sheep anti-rabbit IgG, time of immobilizing sheep anti-rabbit IgG on specific and nonspecific binding of magnetic nanoparticle second antibody in RIA were studied. The results indicated that the average diameter of the decanioc acid-coated Fe3O4 nanoparticle and magnetic nanoparticle second antibody is 10-20 run and around 1000 nm, respectively. The second antibody labeled magnetic nanoparticle can be used in RIA. In conclusion the magnetic nanoparticle second antibody is characterized by the simplicity, time-saving in preparation, low cost and the conveniences of magnetic separation. So it has practical value in medical application.
JIANG Ningyi LIU Sheng ZHU Cansheng WANG Yidong XING Yigang
Issue 11, (2004)
摘要:The objective is to explore the distribution of 99Tcm-HL91 in cerebral ischaemia animal model and evaluate the 99Tcm-HL91 cerebral ischaemia imaging clinicaly. After animal models were established, 99Tcm-HL91 biodistribution was studied by autoradiography. Also, 21 patients who suffered from acute cerebral infarction within 96 hours were studied by 99Tcm-HL91 cerebral imaging. Experimental results show that in the ischemic territory more 99Tcm-HL91 accumulated than in the opposite site by autoradiogram. Using computer-enhanced imaging analysis, the optical density (OD) ratio between target and non-target site was significant. In clinical study, 8 patients had positive imaging showing accumulation of 99Tcm-HL91 in the surrounding of infarction site. It is concluded that 99Tcm-HL91 can be avidly taken up by cerebral ischemic tissue. 99Tcm-HL91 is a potential agent for imaging hypoxic tissue, and SPECT imaging can be used to evaluate cerebral ischaemia.
摘要:A separation reagent of magnetic particle solid-phase second antibody for RIA has been studied. Amine silane modulated magnetic particles were activated using glutaraldehyde and coupled with purified second antibody at different pH values. And the experiment on adsorption of purified second antibody by non-activated magnetic particles at pH 8 was carried out simultaneously. The RIA test demonstrated that the binding percentage of non-activated magnetic particle solid-phase was lower and its stability was less than that of the activated magnetic particle solid-phase . The sensitivity was increased and the correlation coefficient of standard cure was 0.9950 for the activated magnetic particle solid-phase second antibody for CEA RIA. The correlation coefficient of the testing concertration in RIA between separations with liquid-phase and solid-phase was 0.9895. Therefore, it is possible for the magnetic particle solid-phase to be used as a general separation reagent for RIA.
LIU Yongbiao MEI Kai LIU Ying HAO Xingzhi ZHAO Jie ZHANG Xianwen ZHOU Qiang YAO Side
Issue 11, (2004)
摘要:In order to investigate radioprotective effects of interleukin-6 (IL-6) to normal tissues of irradiated tumor-bearing S180 sarcoma mice and its related mechanism, the contents of reactive oxygen species(ROS), malondialdehyde (MDA), activity of glutathione peroxidaes (GSH-Px) and catalase (CAT) in liver, kidney, spleen, lung, brain, marrow were determined. It was found that the content of ROS and MDA increased and the content of GSH-Px and CAT decreased in normal tissues of tumor-bearing S180 sarcoma mice under fractional total-body-irradiation (TB1). With addition of IL-6 the content of ROS and MDA was decreased and the activity of GSH-Px and CAT was increased in liver, spleen, brain, marrow, whereas there is no significant effect on the lung and kidney tissues. It can be deduced that IL-6 has some radio-protective effects to the normal tissue of tumor-bearing mice involved in fractional TBI via scavenging ROS and protecting antioxidant enzymes. As the number, affinity of IL-6 receptor and signal transfer pathway of IL-6 are changeable, the radio-protective effects of IL-6 in various tissues are different.
摘要:Radiation synovectomy is an attractive alternative of surgical or chemical synovectomy for the treatment of various arthritis. The mechanisms, indications, radiopharmaceuticals, techniques, clinical applications, complications and prognosis of radiation synovectomy were summarized and reviewed in this article.
摘要:The analgetic efficiency and adverse effect of 89SrCl2 treatment were observed in 69 patients with metastatic bone tumor from different primary foci. Of 69 patients, pain disappeared completely and metastatic lesions shrinked and disappeared partly in 32 cases; pain abated apparently and analgetic drugs were stopped or reduced in 30 cases; and inefficacy in 7 cases. Of 39 died patients, except ineffective in 7 cases, in the remaining patients either pain abated, analgetics stopped, reduced or life quality improved obviously.
摘要:Radionuclide scintigraphy has its unique value for the diagnosis of inflammatory diseases. The recently developed labeled antibiotics is a new kind of imaging agents in this field. The aim of this paper is to radio label the LVFX with 99Tcm and stannous tartrate as reducing agent The biodistribution of 99Tcm-LVFX in animal model and whole body scintigraphy of animal model were fulfilled. The results showed that labeling method was easy and fast, labelled agent was stable. Both biosdistribution and imaging result showed higher uptake of 99Tcm-LVFX in infection site. It is suggested that technetium labeled LVFX is a potential infection imaging agent.
摘要:One of necessary steps before stem cell transplantation can be pushed on into clinic is finding a non-invasive method to track stem cells implanted inside human body. For high sensitivity and possibility of imaging various molecules within the cells as targets, molecular imaging with SPECT or PET has the most powerful potential to monitor stem cells transplanted in vivo among all the other imaging techniques. The possibility of in vivo tracking of stem cells with various strategies of radionuclide imaging was discussed respectively according to their characteristics and recent development. Receptor imaging may be firstly utilized to solve the problem for its simplicity but poor in its stability and universality. Screening with SELEX techniques, aptamer oligonucleotides specifically targeted to stem cells will be found. Combining antisense imaging with SELEX, the problem of tracing stem cells in vivo would be eventually and thoroughly solved.
关键词:Stem cells;Radionuclide imaging;In vivo tracking
摘要:On the basis of designing the output meter for Type 1600 dredge ship, we have analyzed the relationship between transfer coefficient of γ-ray density meter and radiation source, and the radiation pollution was also considered. All the work was based on the numeric simulation by GEANT4 system. Our work can offer a theoretical guide to the design of y-ray density meter.
关键词:γ-ray density meter;Transfer coefficient;Monte Carlo method
摘要:The principle and experiments on the measurement of grease stain in petroleum pipeline using the thermal neutron gauge were reported. The designed simulated experimental device was aimed at small pipelines. It mainly consists of a thermal neutron beam emissive device and a thermal neutron beam detecting device. The experiment result indicates that it is very sensitive if the thermal neutron beam is used and its measuring accuracy is 1.6mm. If the total neutron beam is used, it is convenient, but is not so sensitive, and its accuracy is 4.4 mm.
ZHANG Xinbao FENG Mingyi ZHANG Yiyun ZOU Xiang WEN Anbang BAI Lixin
Issue 11, (2004)
摘要:7Be fallout is predominantly distributed in the surface soil of 0-20 mm in depth. The highest 7Be content occurs in the surface horizon of 0-2 mm in depth and it exponentially declines with depth. The soil horizon below 20 mm in depth contains little 7Be. Our measurements show that there is a clear difference in 7Be depth distributions in purple soil between grass land and cultivated land in Yanting, Sichuan. 7Be contents in the surface horizon on grassland are higher and decline more rapidly with depth than those in cultivated land, because the cultivated soil is more porous and prone to infiltration of precipitation than the grass soil. 7Be seasonal reference inventories are 117.4 Bq ·m-2 in spring and 169.9 Bq · m-2 in autumn, respectively in Yanting. By comparison with the reported 7Be seasonal reference inventories in other regions in the world, the reference inventories in Yanting are quite lower. Probably this is attributed to the facts that the air moistures of the south-western currents from the low latitude area, which have a low 7Be concentrations, and the air moistures of local evaporation, which contains little 7Be, make great contributions to the precipitation in Sichuan Basin, and that the thick cloud layers and the cloudy climate in the Basin prevent cosmic ray penetration from producing 7Be nuclide.
关键词:Hilly Area of Sichuan Bbasin;7Be;Reference inventory
摘要:We present an introduction to internal polarized gaseous targets, polarization method, polarization measurement method and procedure. To get the total nuclear polarization of hydrogen atoms(including the polarization of the recombined hydrogen molecules) in the target cell, we have measured the parameters relating to atomic polarization and polarized hydrogen atoms and molecules. The total polarization of the target during our measurement is Pr=0.853 ± 0.036.
关键词:Internal polarized gaseous target;High frequency transition;Sextupole magnet