最新刊期
      卷 0 ， 期 0 ， 2020
      • WANG Jie1 LI Honghong1 WANG Feng1 GUO Yuxian1 ZHOU Hongjun1 XUE Song2 LU Qipeng2 1
        Issue 7, (2005)
        摘要：The beamline and the endstation dedicated to soft X-ray absorption supported by Phase II Project of National Synchrotron Radiation Laboratory have been completed. The monochromatic X-ray light can be provided between 100 to 1000 eV, and its flux is over 108 photons/s with a resolving power of 1000 at 1000 eV by using a plane varied-line-space grating monochromator. A focus spot of 3mm in horizontal by 1mm in vertical is obtained. A soft X-ray magnetic circular dichroic spectrum of iron film and near edge absorption spectra of K edges of C, N, O elements have been measured.  
        关键词：Soft X-ray magnetic circular dichroism;Soft X-ray absorption;Plane varied-line-space grating;Beamline;Synchrotron radiation   
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        发布时间：2021-03-12
      • XIE Yaning LIU Tao HU Tiandou ZHANG Jing
        Issue 7, (2005)
        摘要：As an important part of the synchrotron radiation facility, the beam monitor is used to monitor the beam’s position, intensity and distribution in the SR beamline’s diagnostic, commissioning and real time monitoring. A new type of beam monitor based on Si-PIN photodiode has been developed for the newly constructed 1W1B-XAFS beamline. This beam monitor is combined with fixed slit and Be window. Being simple, reliable and low cost, the new beam monitor is mainly used for beamline alignment and monitoring beam intensity. The principle and construction are discussed, and the operation modes and testing results are described in this paper.  
        关键词：Synchrotron radiation;Beam monitor;Beam line;Si-PIN photodiode   
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        发布时间：2021-03-12
      • LING Qing1 JIN Huiyu1 WU Gang1 WANG Qiuping2 1
        Issue 7, (2005)
        摘要：Considering the analytical equations of groove parameters to fourth order and using two spherical mirrors to generate aspherical wavefronts and a spherical blank as a grating blank, we have analyzed the error of groove function and indicated that when the radius of grating blank or the radii of auxiliary mirrors are comparatively small, the series expansion in derivation procedure will introduce comparatively large error. A numerical method based on ray tracing was adopted and the practical groove pattern was calculated. Design example of holographic grating shows that it is necessary to validate the design result of recording parameters through numerical method.  
        关键词：Holographic grating;Aspherical wavefront;Groove function   
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        发布时间：2021-03-12
      • MA Qiaosheng1,2 ZHANG Yonghui1,2 CHANG Anbi1 ZHOU Chuanming3 1
        Issue 7, (2005)
        摘要：After the force on electrons in an annular electron beam was analysed, the condition for propagating an annular electron beam in a periodic permanent magnetic (PPM) field and the shape of the electron beam were derived. It is shown that to propagate an annular electron beam in PPM is possible.  
        关键词：Periodic permanent magnetic (PPM) field;Annular electron beam;Propagation   
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        发布时间：2021-03-12
      • YU Tong1 LI Yaming1 REN Yan1 Wang Enbo2 WANG Wenzhong3 XU Hongying2 1
        Issue 7, (2005)
        摘要：Effects of long-term intake of lanthanum in drinking water on the concentrations of twelve kinds of macro- and trace elements in rat brains were primarily studied by neutron activation analysis. The results show that, along with the elevation of the dose of lanthanum, more and more elements were affected in the rat brain tissues. Compared with control group, the concentrations of five elements were changed in the 1000 mg/L group. These elements have close relations with brain function. Accordingly, intake of lanthanum may have negative effects on brain function.  
        关键词：Rare-earth elements;Lanthanum;Brain;Wistar rat;Neutron activation analysis   
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        发布时间：2021-03-12
      • DENG Guilong1,2 CHEN Chunying1 ZHANG Peiqun1 LIU Yingbin2 ZHAO Jiujiang1 WANG Jianwei2 XU Bin2 PENG Shuyou2 CHAI Zhifang1 1
        Issue 7, (2005)
        摘要：The distribution patterns of 17 elements in the subcellular fractions of nuclei, mitochondria, lysosome, microsome and cytosol of human hepatocellular carcinoma (HCC) and normal liver samples were investigated by using molecular activation analysis (MAA) and differential centrifugation. Their significant difference was checked by the Student’s t-test. These elements exhibit inhomogeneous distributions in each subcellular fraction. Some elements have no significant difference between hepatocellular carcinoma and normal liver samples. However, the concentrations of Br, Ca, Cd and Cs are significantly higher in each component of hepatocarcinoma than in normal liver. The content of Fe in microsome of HCC is significantly lower, almost half of normal liver samples, but higher in other subcellular fractions than in those of normal tissues. The rare earth elements of La and Ce have the patterns similar to Fe. The concentrations of Sb and Zn in nuclei of HCC are obviously lower (P <0.05, P <0.05). The contents of K and Na are higher in cytosol of HCC (P<0.05). The distributions of Ba and Rb show no significant difference between two groups. The relationships of Fe, Cd and K with HCC were also discussed. The levels of some elements in subcellular fractions of tumor were quite different from those of normal liver, which suggested that trace elements might play important roles in the occurrence and development of hepatocellular carcinoma.  
        关键词：Human hepatocellular carcinoma;Trace elements;Molecular activation analysis (NAA);Cellular distribution   
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        发布时间：2021-03-12
      • WANG Huijuan1.2 GUAN Yongjing1 HE Ming1 RUAN Xiangdong2 WU Weiming2 DONG Kejun1 LI Guoqiang1.2 YANG Yaoyun1.3 JIANG Shan1 1
        Issue 7, (2005)
        摘要：There are some interfering backgrounds in the AMS measurements of medium-heavy nuclides. Sometimes the interference will create difficulties in online deciding the detected nuclides with experimental spectra. In order to solve the problem, we set up a method to simulate experimental spectra for medium-heavy nuclides in AMS measurements. This method has been applied in the AMS experiments, and the practical measurements were consistent with the theoretic analysis quite well. It shows that the method can be applied in the nuclide analysis.  
        关键词：AMS;Spectrum analysis;Nuclide measurement;Experimental spectrum   
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        发布时间：2021-03-12
      • DENG Huaifu HU Ping
        Issue 7, (2005)
        摘要：To discuss the applicability of 99TCm-TRODAT-1 SPECT imaging of dopamine transporter in monitoring the state of Parkinson’s disease (PD), 20 patients with PD and a control group of 14 healthy subjects were chosen to conduct dopamine transporter (DAT) imaging by SPECT with 99TCm-TRODAT-1. The radioactive ratio between bilateral striatum and cerebellum and the asymmetry index (AI) of bilateral striatum were computed by using the region of interest (ROI) technology. Meanwhile, the PD patients were classified by the improved Hoehn-Yahr Disability Score and then evaluated by Unified Parkinson’s Disease Rating Scale (UPDRS). The findings show that there is a negative correlation between the bilateral ST/CB mean of the PD and the Hoehn-Yahr grading of the patients’ state of illness, the UPDRS score, the patients’ self-caring ability, the ability to move around. As for the asymmetry index AIPD, there was a positive correlation with the duration of disease, and a significant difference between the PD and the control group, with the former much higher than the latter. Therefore, the dopamine transporter imaging by SPECT with 99TCm-TRODAT-1 can monitor the state of Parkinson’s disease, and show the symptom severity of Parkinson’s disease.  
        关键词：99TCm-TRODAT-1;DAT;Parkinson’s Disease;SPECT   
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        发布时间：2021-03-12
      • ZHANG Wanchun1 LI Sijin1 LIU Jianzhong1 LV Jiyuan2 HU Guang1 WANG Jin1 1
        Issue 7, (2005)
        摘要：To investigate the relationship between the heart-lung ratio (HLR) assessed with exercise 99TcmN-NOET myocardial perfusion imaging and coronary artery disease (CAD), 10 normal volunteers (7 male and 3 female, aged 40.0±5.8 years), and 40 suspected CAD patients (21 male and 19 female, aged 55.2±8.5 years) underwent exercise (30 min)-delayed (2 and 4 h postinjection) 99TcmN-NOETgated myocardial perfusion imaging, and the HLR at different time was calculated. 13 patients among them took the coronary angiography in two months. According to the exercise heart-lung ratio (EXHLR), 50 subjects were divided into two groups. G1 (n=36, EXHLR≥2) included 10 normal volunteers, 5 patients with normal coronary arteries, and the rest 21 patients had no relevant symptom and cardiac event in the follow-up period of 4 to 12 months. The image was normal in all of the subjects in G1. In G2 (n=14, EXHLR<2), 8 patients had significant CAD diagnosed by coronary angiography (≥50% luminal stenosis), 4 of the rest six patients had angina followed with typical ECG changes during the follow-up period. The HLR was of significant difference between the two groups at different time. In G2, nine patients had normal imaging results, of whom four CAD patients were verified by coronary angiography (stenosis 50%—70%), while other five patients had redistribusion or fixed defect. The HLR of the 99TcmN-NOET may be useful as a diagnostic index in CAD because it is more sensitive than myocardial perfusion imaging.  
        关键词：Myocardial perfusion imaging;99TcmN-NOET;Heart-lung ratio   
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        发布时间：2021-03-12
      • LIU Changbin1 TIAN Jiahe1 DENG Jinglan2 QIAO Hongqing2 WANG Jing2 1
        Issue 7, (2005)
        摘要：The preparation of [99mTc(CO)3(OH2)3]+ using carbonyl kits and the labeling of morpholinos (MORF), a DNA analogue, were described. A 25 mer MORF with a primary amine on the 3’ equivalent end attached via a 10 member linker was conjugated with DTPA. The carbonyl kits were reconstituted according to the manufacturer’s recommendation. The reversed phase and size exclusion HPLC indicate that the Tc-carbonyl intermediate’s yield was more than 90%. The DTPA conjugated MORF was successfully radiolabeled, the labeling efficiency ranged (63±7)%, and the specific activity, which was dependent on the specific activity of [99mTc(CO)3(OH2)3]+, was (9.62 ±1.26) GBq/μg. In saline at room temperature and in fresh human serum at 37°C, the radioactivity profile was unchanged over 48 h. This strategy for preparing [99mTc(CO)3(OH2)3]+ using carbonyl kits and labeling MORF with [99mTc(CO)3(OH2)3]+ therefore appears to be suitable for further applications.  
        关键词：Morpholino oligo;([99mTc（CO）3（OH2）3]+);Radiolabeling   
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        发布时间：2021-03-12
      • GUAN Feng1 WANG Quanshi2 WU Hubing2 JIA Zhixin3 1
        Issue 7, (2005)
        摘要：In order to evaluate the clinical value of positron emission tomography (PET) with 2-[18F] fluoro-2-deoxy-D-glucose (FDG) in the postoperative patients with colorectal carcinoma, 59 postoperative patients with colorectal carcinoma were studied with 18FDG PET. 18FDG-PET results were compared with those of CT. The main results are as follows: (1) For 12 local recurrent patients verified by enteroscope or operative pathology, 11 patients were diagnosed by 18FDG PET, 9 patients of whom had metastases at the same time. (2) 18FDG PET found 139 metastases in 35 patients; while CT detected 62 metastases in 30 patients of this group. 18FDG PET also found double carcinoma in 2 patients. (3) For detecting the recurrence of colorectal carcinoma, sensitivity, specificity and accuracy of 18FDG PET is 91.7%, 100% and 98.3%, respectively; which of CT is 76.2%, 61% and 75%, respectively. The sensitivity and accuracy of 18FDG PET in detecting the recurrence of colorectal carcinoma are significantly higher than those of CT. Thus 18FDG PET has superiority in detecting recurrence, local metastasis and qualitative analysis.  
        关键词：Colorectal carcinoma;Positron emission tomography;Computed tomography;Deoxyglucose   
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        发布时间：2021-03-12
      • MENG Qingyong LIU Zhihui XU Meiyi
        Issue 7, (2005)
        摘要：To evaluate the effect of SHP [Sargassum hemiphyllum (Turner) C.Ag. polysaccharides] on splenocytes in irradiated mice, the UDS, DNA and protein’s synthesis of murine splenocytes were detected by 3H-TdR and 3H-TyR incorporation test. Flow cytometry was used to determine the distribution of cell cycles and CD4 expression. The SHP (20 mg/kg and 40 mg/kg) stimulated the synthesis of DNA and proteins in splenocytes of irradiated mice. The SHP (10 —40 mg/kg) significantly enhanced the UDS and CD4 expression of splenocytes in irradiated mice. The SHP (20 mg/kg and 40 mg/kg) might induce the change of cell cycles of splenocytes in irradiated mice; the percentage of cells was decreased in G0/G1 phase and increased in G2/M phase. However, the percentage of cells in S phase for the SHP (10 —40 mg/kg) group was significantly higher than that for the control group. Accordingly, the SHP has a protective effect on splenocytes in irradiated mice.  
        关键词：SHP [Sargassum hemiphyllum (Turner) C.Ag. polysaccharides];Irradiation damage;Splenocytes;Flow cytometry;~3H incorporation   
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        发布时间：2021-03-12
      • JIANG Tao YANG Tongzai WANG Lixiong
        Issue 7, (2005)
        摘要：Stable isotope tracer - 6Li2CO3 (spheroid, 0.5 μm) was prepared using 6LiD as material via re-decomposing reaction. Several conditions were optimized including reactants’ concentration and proportion, reaction temperature and time, and sedimentation time. The structure of 6Li2CO3 was characterized by FTIR (Fourier transform infrared radiation), XRD (X-ray diffraction) and SEM (Scanning electron microscope).  
        关键词：~6Li;Isotope;Aerosol;Tracer   
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        发布时间：2021-03-12
      • XIAO Kunxiang ZHOU Minggui TAN Xiaohua MEI Lin LIANG Chuan
        Issue 7, (2005)
        摘要：A miniature Penning ion source including a φ 10 mm anode cup inside, used for small well logging neutron tube, was developed. Both electromagnetic field and geometry of the ion source were designed reasonably. The test results show that the source has good current stabilization, high neutron yield and good performance. So it can meet the need of a small well logging neutron tube.  
        关键词：Ion source;Anode;Electromagnetic field;Neutron tube   
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        发布时间：2021-03-12
      • DONG Chengfu SU Hong LI Xiaogang MA Xiaoli JIN Genming LI Yong PENG Yu LI Suqin
        Issue 7, (2005)
        摘要：A new multiple charge sensitive preamplifier developed recently is introduced in this paper. This preamplifer can provide 8CH for most number. A new design is adopted to implement this preamplifer which mainly consists of slow noise N-FET transistor and an integrated low noise, high-speed operational amplifer. The equivalent inpout noise is ≤2.2 keV at 0pF. This preamplifer features simple structure, small dimensions, fast risetime of output pulse, low noise, excellent stability. We introduced the structure and features of this preamplifier in detail in this paper.  
        关键词：Charge sensitive;Preamplifier;Multiple   
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        发布时间：2021-03-12
      • MA Qingli Nasseri M M YIN Zejie ZHU Daming WU Xiaoyi
        Issue 7, (2005)
        摘要：Fundamental characteristics of the plastic-scintillating fiber (PSF) for wide energy range of electromagnetic radiation (X & γ) have been studied to evaluate possibility of using the PSF as an imaging detector for industrial purposes. Monte-Carlo based simulation program (GEANT4.5.1, 2003) was used to generate the data. In order to evaluate image quality of the detector, the fiber array was irradiated under high energy and flux and Signal-to-Noise Ratio (SNR), Detector Quantum Efficiency (DQE) and Modulate Transfer Function (MTF) were obtained. From the analysis, we have found that some properties of PSF are different from those of traditional screen-film, and can conclude that it is possible to apply PSF to the imaging of high-energy incident beam.  
        关键词：Signal-to-Noise Ratio (SNR);Detector Quantum Efficiency (DQE);Scintillating fiber array;Imaging detector;Geant 4   
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        发布时间：2021-03-12
      • QU Guopu LING Qiu GUO Lanying ZHAO Lihong CHEN Jianzhen CHEN Conggui
        Issue 7, (2005)
        摘要：Problems of spectrum-drifting and spectrum stabilization in the 13N monitoring instrument were discussed and the measuring principle including block-diagram was given. The nonlinear relationship between the energy and temperature was measured. As the non-linearity method is applied, the 511 keV γ-ray’s peak location drifts only <±1 channel for the temperature change from 10℃ to 45℃.  
        关键词：13N monitoring instrument;Spectrum-drifting;Spectrum stabilization;Energy non-linearity   
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        发布时间：2021-03-12
      • MAO Yahong1 LIU Yigang2 FU Yuchuan3 LIN Libin3 1
        Issue 7, (2005)
        摘要：In the past, the radiological dose model for soil (the soil’s dose model) was used to calculate the doses of decorative building materials, because no model suited to these materials was established. With the help of Monte Carlo method, we have proposed a new model to calculate the absorbed dose rates in air for decorative building materials. Values calculated by the new dose model, though much diverse from those by the soil’s dose model, are very close to the measured values. It is therefore concluded that the soil’s dose model is usually not suitable for estimating radiological doses from decorative building materials.  
        关键词：Decorative building materials;Radiation;Dose model   
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        发布时间：2021-03-12
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