基于SiPM的塑料闪烁光纤剂量计的研制

杨翠萍; 辛杰; 周冬冬; 李一秋; 柴林; 尤思梅; 张保国; 文万信; 张明; 王仁生

doi:10.11889/j.0253-3219.2019.hjs.42.100402

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基于SiPM的塑料闪烁光纤剂量计的研制

核电子学与仪器 | 更新时间：2024-10-25

- 基于SiPM的塑料闪烁光纤剂量计的研制
- Development of a SiPM-based practical plastic scintillation fiber dosimeter
- 核技术 2019年42卷第10期
- 作者机构：
  
  1.苏州大学医学部放射医学与防护学院苏州 215123
  2.江苏省高校放射医学协同创新中心苏州 215123
  3.苏州大学附属第一医院苏州 215006
  4.中国计量科学研究院电离辐射计量科学研究所北京 100029
  5.南京脑科医院南京 210029
- 作者简介：
  
  杨翠萍，女，1992年出生，2017年毕业于徐州医科大学，现为硕士研究生，研究领域为医学物理
  王仁生，E-mail:wrs16@suda.edu.cn
- 基金信息：
  
  国家重点研发计划(2017YFF0206205);国家自然科学基金青年基金项目(11605119);江苏省自然科学基金青年项目(BK20160304);国家博后基金面上项目(2017M621818)
- DOI：10.11889/j.0253-3219.2019.hjs.42.100402
  中图分类号： R811.1
- 收稿日期：2019-07-03，
  
  修回日期：2019-07-28，
  
  纸质出版日期：2019-10-13
- 稿件说明：
移动端阅览
杨翠萍,辛杰,周冬冬等.基于SiPM的塑料闪烁光纤剂量计的研制[J].核技术,2019,42(10):39-45.

YANG Cuiping,XIN Jie,ZHOU Dongdong,et al.Development of a SiPM-based practical plastic scintillation fiber dosimeter[J].NUCLEAR TECHNIQUES,2019,42(10):39-45.
杨翠萍,辛杰,周冬冬等.基于SiPM的塑料闪烁光纤剂量计的研制[J].核技术,2019,42(10):39-45. DOI： 10.11889/j.0253-3219.2019.hjs.42.100402.

YANG Cuiping,XIN Jie,ZHOU Dongdong,et al.Development of a SiPM-based practical plastic scintillation fiber dosimeter[J].NUCLEAR TECHNIQUES,2019,42(10):39-45. DOI： 10.11889/j.0253-3219.2019.hjs.42.100402.

摘要

放疗过程中，利用塑料闪烁光纤剂量计(Plastic Scintillator Fiber Dosimeters

PSFDs)对患者关键健康组织及肿瘤进行实时、高位置分辨的介入式剂量测量是质量保证（Quality Assurance

QA）最直接的手段之一。为研究PSFDs的实际应用情况，研制一套基于连续剂量读出的实用型塑料闪烁光纤剂量计。该剂量计以硅光电倍增管（Silicon Photomultiplier

SiPM）作为光电转换器件，通过测量SiPM输出电流实现剂量测量。利用发光二极管（Light Emitting Diode

LED）脉冲光源与小动物图像引导放射治疗机

对该剂量计的时间稳定性、重复性、温度响应、白光纤曲率响应以及动态范围等进行了系统研究。实验结果表明：恒温20 ℃，剂量计8 h内连续工作，输出电流变化小于1%，32 h间断工作输出电流变化小于0.5%；温度变化小于0.5 ℃，白光纤曲率半径大于11 cm，输出电流变化小于1%；剂量计线性动态范围可达100~9 000 cGy∙min

-1

。该剂量计基本满足临床剂量验证的要求。

Abstract

Background

A real-time

high position resolved in-vivo dose measurement of critical health tissues and tumors is one of the most direct quality assurance (QA) tools in the radiotherapy. Plastic scintillator fiber dosimeters (PSFDs) have great advantages in dose verification due to its small size

good radiation resistance and good tissue equivalence.

Purpose

This study aims to develop a plastic scintillation fiber dosimeter （PSFD） based on silicon photomultiplier (SiPM)， and investigate its performance in clinical applications.

Methods

With a stable LED pulse optical source

the leakage current of SiPM was measured by the picoammeter. Time stability and repeatability of the dosimeter

temperature response and the influence of the transmission fiber curvature on the SiPM leakage current were systematically studied. The dynamic range of the dosimeter was measured by using a small animal radiotherapy machine and LED pulse optical source.

Results

The results show that the leakage current changes

1% when the dosimeter works continuously for 8 h at constant temperature of 20 ℃

and the leakage current changes

0.5% during 32 h of intermittent operation. When the temperature change is less than 0.5 ℃

or the transmission fiber radius of curvature is greater than 11 cm

the output current change is less than 1%. The linear dynamic range of the dosimeter measurement is 100~9 000 cGy∙min

-1

Conclusions

The developed dosimeter basically meets the accuracy requirements of the clinical dose verification.

关键词

Keywords

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