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BL17U短波长X射线聚焦方案优化
Optimized focusing plan for short X-ray wavelengths mode at BL17U in SSRF
- 核技术 2018年41卷第5期 文章编号：050102
- 作者机构：
1.中国科学院上海应用物理研究所 张江园区 上海 201204
2.中国科学院大学 北京 100049
- 作者简介：
[ "钟长游, 男, 1992年出生, 2015年毕业于南华大学, 现为硕士研究生, 从事同步辐射光束线技术研究", "ZHONG Changyou, male, born in 1992, graduated from Nanhua University in 2015, master student, focusing on beam line technology of synchronous radiation" ]
何建华, E-mail:hejianhua@sinap.ac.cn HE Jianhua, E-mail:hejianhua@sinap.ac.cn
- 基金信息：中国科学院青年创新促进会(2015213);国家自然科学基金(U1632126)
DOI：10.11889/j.0253-3219.2018.hjs.41.050102
中图分类号： TL99收稿日期：2017-12-04，
修回日期：2018-01-30，
纸质出版日期：2018-05-10
- 稿件说明：
移动端阅览
钟长游, 汪启胜, 刘科, 等. BL17U短波长X射线聚焦方案优化[J]. 核技术, 2018,41(5):050102
Changyou ZHONG, Qisheng WANG, Ke LIU, et al. Optimized focusing plan for short X-ray wavelengths mode at BL17U in SSRF[J]. Nuclear techniques, 2018, 41(5): 050102
钟长游, 汪启胜, 刘科, 等. BL17U短波长X射线聚焦方案优化[J]. 核技术, 2018,41(5):050102 DOI： 10.11889/j.0253-3219.2018.hjs.41.050102.
Changyou ZHONG, Qisheng WANG, Ke LIU, et al. Optimized focusing plan for short X-ray wavelengths mode at BL17U in SSRF[J]. Nuclear techniques, 2018, 41(5): 050102 DOI： 10.11889/j.0253-3219.2018.hjs.41.050102.
摘要
蛋白质数据库中超过80%的蛋白质都是用X射线衍射解出的结构，其中最常用的波长是0.0972 nm。有研究表明短波长X射线可以减少晶体的辐射损伤，提高X射线衍射数据的质量，为了在上海同步辐射光源生物大分子线站BL17U上进一步研究短波长X射线测定蛋白质结构，需要先对其能区进行拓展。基于复合折射透镜（Compound Refractive Lens，CRL）聚焦X射线的原理，讨论了在BL17U上用其聚焦短波长X射线的可行性。通过引入接受率
R
这一物理量计算了单一结构不同曲率半径的CRL聚焦光子后的通量和通量密度，同时也计算了级联式紧密接触型CRL和级联式相间型CRL两种方式的聚焦的效果。在充分考虑聚焦效果、实验站布局等因素，提出在BL17U聚焦短波长X射线的最佳方案，用31片半径50 μm的透镜理论上可以将25keV的光子聚焦，得到的通量密度3.2018×10
14
s
-1
·mm
-2
。通过这些理论计算可以为BL17U研究短波长X射线测定蛋白质结构做前期准备。
Abstract
Background
2
More than 80% of the protein in the protein database is solved by X-ray diffraction. The most commonly used wavelength is 0.0972 nm. Studies have shown that short-wavelength X-rays can reduce the radiation damage of crystals and improve the quality of X-ray diffraction data.
Purpose
2
In order to collect X-ray diffraction data from protein crystals with shorter wavelength at beamline BL17U in Shanghai Synchrotron Radiation Facility (SSRF)
our first priority is to extend its energy range to 25 keV using compound refractive lens (CRL).
Methods
2
The flux rate and flux density of the CRL focused photon with different curvature radius of a single structure are calculated by introducing the acceptance rate
R
. The close contact type CRL and the interphase type CRL are also calculated.
Results
2
Focusing on the factors such as the focusing effect and the layout of the experimental station
we propose the best solution for focusing short-wavelength X-rays in BL17U. Using 31 lenses with a radius of 50 μm can obtain 3.2018×10
14
s
-1
·mm
-2
at 25 keV theoretically.
Conclusion
2
Through these theoretical calculation
we can prepare for collect protein crystal data using short X-ray wavelengths in BL17U.
关键词
Keywords
references
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