Background: The multi-leaf collimator (MLC) is one of key components of modern medical accelerators for Intra-operative Radiation Therapy (IORT). The stability and accuracy of MLC’s control system will insure patients’ life security during radiation therapy. Comparing with the world’s top level

domestic MLC technologies falls behind not only in stability but also in accuracy. Purpose: This study aims to design a MLC control system satisfying the requirements of developing the first domestic IORT accelerator and closing the gap with the world advanced level. Methods: The MLC control system was reconfigurated by the System-on-a-Programmable-Chip (SOPC) technique based on the traditional MLC control system. By adding new function model

preventing Electromagnetic Interference (EMI) and other ways

the newly developed MLC control system can fulfill IORT accelerator’s function and mechanical installation requirements. Results and Conclusion: The test results show that the control system possess properties of full functionalities

redundant position feedback

conformity to national standards of medical instruments and insuring the R&D of IORT accelerator. Abstract