<sup>99m</sup>Tc-MIBI SPECT与<sup>18</sup>F-FDG PET诊断胶质瘤复发及恶变对比分析

赵军; 杨乃明; 李家敏; 吴金陵; 孙爱君; 王明芳; 宋述强

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^99mTc-MIBI SPECT与¹⁸F-FDG PET诊断胶质瘤复发及恶变对比分析

更新时间：2021-04-09

- ^99mTc-MIBI SPECT与¹⁸F-FDG PET诊断胶质瘤复发及恶变对比分析
- Comparison of ^99mTc-sestamibi SPECT and ¹⁸F-FDG PET imaging in the diagnosis of recurrence and malignancy of glioma
- 核技术 1998年第5期
- 作者机构：
  
  淄博万杰医院,淄博,255202
- 作者简介：
- 基金信息：
- DOI：
  中图分类号： R739.4
- 纸质出版日期：1998-05-01
- 稿件说明：
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[1]赵军,杨乃明,李家敏,吴金陵,孙爱君,王明芳,宋述强.~(99m)Tc-MIBI SPECT与~(18)F-FDG PET诊断胶质瘤复发及恶变对比分析[J].核技术,1998(05):271-274.

Comparison of ^99mTc-sestamibi SPECT and ¹⁸F-FDG PET imaging in the diagnosis of recurrence and malignancy of glioma[J]. Nuclear techniques, 1998, (5): 271-274.
[1]赵军,杨乃明,李家敏,吴金陵,孙爱君,王明芳,宋述强.~(99m)Tc-MIBI SPECT与~(18)F-FDG PET诊断胶质瘤复发及恶变对比分析[J].核技术,1998(05):271-274. DOI：

Comparison of ^99mTc-sestamibi SPECT and ¹⁸F-FDG PET imaging in the diagnosis of recurrence and malignancy of glioma[J]. Nuclear techniques, 1998, (5): 271-274. DOI：

摘要

对28例经过治疗的胶质瘤患者进行Gd－DTPAMRI和18F－FDGPET显像，其中14例同时进行99mTc－MIBISPECT显像，并与治疗前解剖影像对比。PET结果发现14例高代谢，10例低代谢，4例瘤灶中心坏死，周边FDG环状摄取。8例首次手术病理Ⅰ－Ⅱ级星形细胞瘤患者中5例为高代谢。18F-FDGPET和99mTc－MIBISPECT诊断胶质瘤复发及恶变的灵敏度依次为93．3％、91．7％。准确性依次为94．1％、85．7％．PET比MRI增强扫描及MIBISPECT显像更能准确鉴别胶质瘤的复发与恶变，MIBISPECT检出的病变范围比PET大。

Abstract

This study compares the diagnostic value of 18F-FDG PET and 99mTc-MIBISPECT imaging in the diagnosis of recurrence and malignancy of glioma. 28 patientswith glioma post treatment were performed by MRI or/and CT and 18F-FDG PETimagmg

and 14 of them were also performed by 99mTc-MIBI SPECT. On PET scans

10 patients were hypometabolic

4 patients were central non-metabolic withperipheral rm FDG uptake

14 patients were hypermetabolic. Out of 8 patients withastrocytoma Ⅰ - Ⅱ grade confirmed by operation

5 ones showed hypermetabolic

indicating malignant degeneration of low-grade glioma. The sensitivity and accuracyof 18F-FDG PET and 99mTc-MIBI SPECT in the diagnosis of recurrence andmalignant degeneration of glioma were 93.3%

94.1% and 91.7%

85.7% respectively.FDG PET imaging is the most accurate method in the detection of recurrence andmalignant degeneration of low-grade glioma

compared with MRI enhancement and99mTc-MIBI SPECT. The extent of lesion site detected by MIBI scans is usuallybigger than FDG PET imaging.

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99mTc-MIBI SPECT与18F-FDG PET诊断胶质瘤复发及恶变对比分析

Comparison of 99mTc-sestamibi SPECT and 18F-FDG PET imaging in the diagnosis of recurrence and malignancy of glioma

DOI：

摘要

Abstract

关键词

Keywords

references

^99mTc-MIBI SPECT与¹⁸F-FDG PET诊断胶质瘤复发及恶变对比分析

Comparison of ^99mTc-sestamibi SPECT and ¹⁸F-FDG PET imaging in the diagnosis of recurrence and malignancy of glioma