Evaluation of myocardiotoxicity on adriamycin（ADM） with SPECT cardiac blood pool imaging was presented. SPECT was done to monitor left ventricular function in 49 patients with Non-Hodgkin’s Lymphoma and small cell carcinoma

they were treated with ADM of which the accumulation dose were over 300mg/m2. The results showed that parameters of EF

PER and PFR before and after treatment with ADM were 57±6%

3.08±0.63EDV. s-1

2.99±0.23EDV. s-1 and 50±11%

2.25±0.66EDV. s -1

2.53±0.35EDV. s-1 respectively. The difference of these data are significant （P<0.05）. The larger the accumulative dose of ADM

the more the parameters decrease

among them PFR is the most sensitive one. It was concluded that SPECT measurement of left ventricular function is a sensitive and useful method in monitoring ADM myocardiotoxicity.