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福建医科大学附属第一医院
纸质出版日期:1997-05-01
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[1]林好学,谢志淳,林军,缪蔚冰,彭接权.45例 ~(131)I-MIBG 肾上腺髓质显像临床应用[J].核技术,1997(05):37-41.
Lin Haoxue Xie Zhichun Lin Jun Miao Weibing Peng Jiequan. Clinical use of 131 I-MIBG adrenal medullary imaging in 45 patients[J]. Nuclear techniques, 1997, (5).
用131I-MIBGSPECT对45例病人肾上腺髓质显像,结果原发性高血压组(n=20)75%患者(15/20)48h呈稀疏显像;肾上腺髓质增生组(n=6)患者腺体均增大,24h即成较清晰至清晰显像;嗜铬细胞瘤组(n=10)24h即成显著显像。ECT显像结果与病理/手术一致。表明该技术对嗜铬细胞瘤(尤其无症状、异位、多发、恶性、转移性及家族性)定位与定性诊断的敏感性,特异性及准确性都高于B超、CT与尿VMA测定。指出心肌不显像可作为间接诊断嗜铬细胞瘤的有价值辅助诊断指标。
Adrenal medullary imaging with 131 I-MIBG was carried out in 45 patients
among them 20 primary hypertension
10 pheochromocytoma
6 adrenal medullary hyperplasia
3 adrenal carcinoma
1 adrenal ganglioma and 5 after adrenaoectomy. The results of examination coincided with pathological
surgical and clinical diagnosis. The sensitivity
specificity and accuracy of the imaging were higher than CT
UT and urinary VMA determination. Finally
it was pointed out that non-imaging of heart can be used as an indirect indication for the diagnosis of pheochromocytoma.
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