Tracer experiment showed that 99mTc-PAHIDA was distributed predominantly in kidney.The distribution in other tissue was in the following descending order: heart
gastrointestinal tract
liver
spleen
muscle
adipose tissue
testes
and brain. The smaller the intravenous dose
the lower the proportion of the drug was combined to plasma protein and the more the drug was distributed in kidney.Excretion of 99mTc-PAHIDA via urine was rapid and was in its original form as shown by radiochromatogrphy.