activited levels of platelet granule membrane protein(GMP-140) in coronary heart disease(CHD) were assayed by RIA. The results showed that the levels of GMP-140 with CHD were higher than that of controls (P>0.001).The levels of GMP-140 with AMI treated with urokinase for thrombolysis in 12 hours were considerably lower than that one hour before treatment.Therefore
the measurement of GMP-140 with CHD is of great clinical value in diagnosing and differentiating AMI
especially
in analysing pathogeny
in monitoring curative effect and predicting prognosis for AMI.