Diagnostic significance of elements in hair with esopphageal cancer by computerized pattern recognitiona and PIXE[J]. Nuclear techniques, 1994, (3).DOI:
The concentration of 12 elements in 414 hair samples of male adults from esophageal cancer group(ECG)
serious esophagus epithelial cell hyperplasia group(SEECHG)and normal control group (NCG) were determined by PIXE. By a t-test it is found that significant differences exist for 10 elements(St
S
Ca
Cr
Mn
Fe
Ni
Cu
Pb and Sr) between ECG and NCG and for 9 elements (St
P
S
Ca
Cr
Mn
Fe
Ni and Zn) between SEECHG and NCG. The three types of persons mentioned above were classified by Mahalanobis distance discriminatory analysis (one of thecomputerized pattern recognition methods).The results show that the ratio of correct classification is around 72%
suggesting that this may become a promising method for the early diagnosis of esophageal cancer.