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1. 上海医科大学附属肿瘤医院
2. 上海纺织局第一职工医院
3. 上海医科大学附属肿瘤医院上海纺织局第一职工医院
纸质出版日期:1994-11-01
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[1]章英剑,邵鹏,王俊玲,蒋长英,储绍琳.用~(99m)Tc-过锝酸盐甲状腺/本底比值快速诊断甲状腺功能亢进[J].核技术,1994(11):672-676.
Rapid diagnosis of hyperthyroidism with 30min ̄(99m)Tc pertechnetate thyroid uptake ratio[J]. Nuclear techniques, 1994, (11).
197例甲状腺疾病患者和10例非甲状腺疾病患者接受了甲状腺显像。用甲状腺/本底比值(以下简称比值)评价其功能,其中103例和96例分别与摄碘率、摄锝率进行了比较。结果表明,各种不同本底ROI下得到的比值与3、24h摄碘率均有良好相关(r=0.74—0.83),差别无显著性(P>0.05),但与甲状腺距15宽5像素的“W”形本底ROI的回归系数有显著性差别(P<0.01),且与摄锝率良好相关(r=0.82,P<0.01)。摄碘正常组(n=59)比值平均为7.2±0.6(以下同),增高组(n=21)为17.8±1.8,减退组(n=23)为3.4±0.9,对照组(n=10)为6.3±1.5,前三者均数的差别有显著性(P<0.01),正常与对照组无明显差别(P>0.05)。增高组与其它各组几乎无交叉。而摄锝率结果较为偏态,交叉大。若以比值>11.02为异常增高,则甲亢诊断阳性率为95.7%(22/23),与摄碘率检查符合率为92.2%(95/103)。本文提示用99mTC-过锝酸盐甲状腺/本底比值能快速诊断甲状腺功能亢进。
patients with a variety of thyroid disorders and 10 patients of non-thyroid-diseases performed routine thyroid foraging 30 min after an intravenous injection of 74-185MBq 99mTc pertechnetate. Thyroid function was estimated with thyroid/background ratio. The results showed that the thyroid uptake ratio had good correlation both with the thyroid uptake rate of 3
24h 131 I (n= 103) and 30min 99mTc pertechnetate (n=96) (r=0.74- 0.83). The thyroid uptake ratio in groups of hyperthyroidism
euthyroid and hypothyroidism
were 17.8 ± 1.8
7.2 ± 0.6 and 3.4 ± 0.9respectively(P<0.01 using the t-test). Thereby
it could be used for the rapiddiagnosis of thyroid function.
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