he immunoglobulin G(IgG) was directly labelled with 99mTc by prereduction of IgG with dithiothreitol and redution of pertechnetate wiht a stannous kit. The radiochemical purity was over 95% .Hence no purification was needed
High labelling dfficiency could be obtained with a variety of weak exchange ligands
such as PYP
MDP
GH
Phytate and EHIDA kits
But DTPA was not effective substance for this procedure. iN vitro studies and the animal imaging showed that 99mTc -IgG was stable useful in diagnosis of focal experimental abscess.