861消瘤片对子宫肌瘤患者血浆性激素及肌瘤组织受体含量的影响

周俊; 沈仲理; 宫斌; 乐秀珍

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861消瘤片对子宫肌瘤患者血浆性激素及肌瘤组织受体含量的影响

更新时间：2021-04-09

- 861消瘤片对子宫肌瘤患者血浆性激素及肌瘤组织受体含量的影响
- The effect of "861 Xiao Liu Pian" on the level of sexual hormones in plasms and the receptors in myofibroma tissues of patients
- 核技术 1993年第5期
- 作者机构：
  
  1. 上海中医学院附属岳阳医院
  2. 上海中医学院
  3. 上海中医学院附属岳阳医院,上海,200031
- 作者简介：
- 基金信息：
  
  卫生部“七·五”攻关课题资助()
- DOI：
  中图分类号：
- 纸质出版日期：1993-05-01
- 稿件说明：
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[1]周俊,沈仲理,宫斌,乐秀珍.861消瘤片对子宫肌瘤患者血浆性激素及肌瘤组织受体含量的影响[J].核技术,1993(05):299-302.

Zhou Jun Shen Zhongli Gong Bin Le Xiuzhen. The effect of "861 Xiao Liu Pian" on the level of sexual hormones in plasms and the receptors in myofibroma tissues of patients[J]. Nuclear techniques, 1993, (5): 299-302.
[1]周俊,沈仲理,宫斌,乐秀珍.861消瘤片对子宫肌瘤患者血浆性激素及肌瘤组织受体含量的影响[J].核技术,1993(05):299-302. DOI：

Zhou Jun Shen Zhongli Gong Bin Le Xiuzhen. The effect of "861 Xiao Liu Pian" on the level of sexual hormones in plasms and the receptors in myofibroma tissues of patients[J]. Nuclear techniques, 1993, (5): 299-302. DOI：

摘要

用中药861消瘤片治疗子宫肌瘤患者50例（子宫体包括肌瘤体积不超过三个月妊娠子宫大小）

六个月后

子宫肌瘤消失率为26％

缩小率为46％。对22例肌瘤患者于治疗前后测定了血浆中FSH、LH、E

、P、T含量

发现治疗前患者P含量明显低于正常妇女（p

0.05）。治疗后分泌期P含量升高（p

0.05）。对30例肌瘤组织中EcR、EnR含量进行了测定

中药组与对照组比较

EcR、EnR含量均明显降低（p

0.05）。临床和实验研究提示:该药治疗机理可能与调节内分泌功能及抑制肌瘤组织中ER水平有关。

Abstract

50 patients suffering from uterine myofibroma were treated with "861 Xiao Liu Pian". Six months after the treatment

the ratio of disappearance of the myofibroma was 26% and the reduction ratio was 46%. The levels of FSH

P and T in plasma of 22 patients were determined before and after the treatment. It was found that the amount of P before treatment was obviously less than that of the control women （n=15

p<0.05） and the amount of P during secretion period after the treatment rose remarkably （p< 0.05）. In addition

the densities of EnR in myofibroma tissues of 30 patients were significantly reduced in the treated group than in control group（p<0.05）. The present work suggested that the mechanism of the action of "861 Xiao Liu Pian" might probably be the regulation of endocrine function and the suppression of ER level in myofibroma tissues.

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