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1. 上海第二医科大学附属仁济医院
2. 天津德普(DPC)公司,上海,200001
纸质出版日期:1993-05-01
移动端阅览
[1]袁济民,朱翠英,崔文儒.TSH(IRMA)测定的临床应用及其评价[J].核技术,1993(05):279-282.
Yuan Jimin Zhu Cuiying Cui Wenru. Clinical application and evaluation of TSH(IRM A) determination[J]. Nuclear techniques, 1993, (5): 279-282.
报告了714例病人和303名正常人的TSH(IRMA)测定结果。正常值为0.3—5.0mU/l
205例甲亢、56例早期甲亢和67例亚临床甲亢病人的测定值为ND(
<
0.02mU/l)—0.69mU/l
其中95%患者
<
0.3mU/l
约2/3患者的TSH水平处于ND状态。对甲亢治疗病人的监测显示
TSH是最后恢复正常的参数
故其对甲亢诊断和转归监测的敏感性均高于FT
3
。从64例TSH(IRMA)测定和TRH兴奋试验的比较显示了两者结果的高度一致
可大大减少TRH兴奋试验的应用
因此
TSH(IRMA)测定的建立和应用引起了甲状腺功能诊断程序的战略性改变。
The serum TSH level of 303 healthy persons ranged from 0.3-5.6 mU/1 and 205 cases of hyperthyroidism
56 cases of early stage hyperthyroidism
67 cases of subclinical hyperthyroidism ranged < 0.02-0.69 mU/1 were reported. TSH levels in 95% patients of subclinical hyperthyroidism was <0.3 mU/1 and about 2/3 patients was nondetectable(<0.02 mU/1). For the thyrotoxicosis after therapy
TSH is the best parameter for the monitoring of its recurence. And better than FT3 as far as the sensitivity for the diagnosis and prognostic monitoring of thyrotoxicosis is concerned. Comparison of TSH(64 cases) and TSH stimulating test was highly correlated
therefore the application of latter test can be greatly reduced. And also the establishment and application of TSH(IRMA) gives a strategic change of the diagnostic procedure of thyroid function test.
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