This paper reports the contents of lymphocyte glucocorticoid receptors （GCR） in 48 patients with nephrotic syndrome

using radioligand binding assay of receptors. The contents of GCR in patients with nephrotic syndrome was 18936±10097 binding sites/cell in adult and 9274 ± 3847 binding sites/cell in children. There was significant difference between them （P<0.05）. The contents of GCR in children and adult with nephrotic syndrome were significantly higher than that in normal ones （p<0.05）. There were no significant difference between the contents of GCR in different sex and age groups （p> 0.05）. The contents of GCR in patients with nephrotic syndrome was significantly increased. This result suggested that contents of GCR in lymphocytes are correlated with nephrotic syndrome

and the treatment of nephrotic syndrome may be effective by hormaonal therapy.