The effect of Heart- and Kidney- Benefiting Chinese Herbal Medicines on the function of adrenergic receptors in brain tissues of analogue dementia rats
Gong Bin Mo Qizhong Fang Jun Chen Kunhua Li Weixiong Wang Jumei Kuang Xingwei Chen Rong. The effect of Heart- and Kidney- Benefiting Chinese Herbal Medicines on the function of adrenergic receptors in brain tissues of analogue dementia rats[J]. Nuclear techniques, 1992, (5): 304-308.
Gong Bin Mo Qizhong Fang Jun Chen Kunhua Li Weixiong Wang Jumei Kuang Xingwei Chen Rong. The effect of Heart- and Kidney- Benefiting Chinese Herbal Medicines on the function of adrenergic receptors in brain tissues of analogue dementia rats[J]. Nuclear techniques, 1992, (5): 304-308.DOI:
Analogue dementia modelof rats was produced by electrolytic lesion of brain. α1 -adrenergic receptors were assayed by radioligand binding assay (RRBA). It was found that Bmax of α1 receptors was decreased obviously in cerebral certex
hippo- campus and cerebellum of analogue dementia rats and was raised obviously by Heart-and Kidney- Benefiting Chinese Herbs as well as by Hydergin.The electrolytic lesion did not change the activity of MAO-B in model rat brains. Neither Heart- and Kidney- Benefiting Chinese Herb Medicines nor Hydergin showed marked effect on brain MAO-B activity of the model rats.