The development and application of the radiation-induced labelling method are described. The method is an especial technique for preparing tritium labelled compounds. Since Wilzbach’s gas exposure method was set up in 1957

much improvement has been made such as high frequency electrical dis-charge method

microwave discharge activation （MDA） method and ion beam tritium labelling method. Because of its distinctive features and the use of tritium nuclear resonance spectroscopy （3H-NMR）

the radiation-induced labelling method has become in common use for preparing tritium labelled compounds.