<sup>18</sup>F-FDG PET显像在结直肠癌术后诊断中的临床应用

关锋; 王全师; 吴湖炳; 贾志新

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¹⁸F-FDG PET显像在结直肠癌术后诊断中的临床应用

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- ¹⁸F-FDG PET显像在结直肠癌术后诊断中的临床应用
- Clinical value of ¹⁸FDG PET in postoperative diagnosis of colorectal carcinoma
- 核技术 2005年第7期
- 作者机构：
  
  1. 吉林大学第一医院
  2. 南方医科大学南方医院PET中心
  3. 武警内蒙古总队医院,长春,130021
  4. ,呼和浩特,010031
- 作者简介：
- 基金信息：
- DOI：
  中图分类号： R735.3
- 纸质出版日期：2005-07-01
- 稿件说明：
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[1]关锋,王全师,吴湖炳,贾志新.~(18)F-FDG PET显像在结直肠癌术后诊断中的临床应用[J].核技术,2005(07):538-541.

GUAN Feng1 WANG Quanshi2 WU Hubing2 JIA Zhixin3 1. Clinical value of ¹⁸FDG PET in postoperative diagnosis of colorectal carcinoma[J]. Nuclear techniques, 2005, (7): 538-541.
[1]关锋,王全师,吴湖炳,贾志新.~(18)F-FDG PET显像在结直肠癌术后诊断中的临床应用[J].核技术,2005(07):538-541. DOI：

GUAN Feng1 WANG Quanshi2 WU Hubing2 JIA Zhixin3 1. Clinical value of ¹⁸FDG PET in postoperative diagnosis of colorectal carcinoma[J]. Nuclear techniques, 2005, (7): 538-541. DOI：

摘要

探讨18F-FDGPET显像在结直肠癌术后诊断中的临床应用价值。59例结直肠癌术后患者均行18F-FDGPET全身显像

并与同期CT进行对比。结果是:①临床明确诊断为局部复发的12例患者（经纤维肠镜活检病理或手术病理证实）

PET明确诊断11例

并同时检出局部复发伴转移9例。②PET于35例病人中发现139个转移灶

其中30例同期进行了CT检查

共发现62个转移灶。2例PET意外发现双重癌。③PET显像对结直肠癌复发检出的灵敏度为91.7%

特异性为100%

准确性为98.3%。而同期腹部及盆腔CT对结直肠癌局部复发检出的灵敏度为76.2%

特异性为61.0%

准确性为75%。可见18F-FDGPET显像对结直肠癌复发的检出明显高于CT

对复发、转移灶的定位、定性上具有优势

且有全身意义。

Abstract

In order to evaluate the clinical value of positron emission tomography (PET) with 2-[18F] fluoro-2-deoxy-D-glucose (FDG) in the postoperative patients with colorectal carcinoma

59 postoperative patients with colorectal carcinoma were studied with 18FDG PET. 18FDG-PET results were compared with those of CT. The main results are as follows: (1) For 12 local recurrent patients verified by enteroscope or operative pathology

11 patients were diagnosed by 18FDG PET

9 patients of whom had metastases at the same time. (2) 18FDG PET found 139 metastases in 35 patients; while CT detected 62 metastases in 30 patients of this group. 18FDG PET also found double carcinoma in 2 patients. (3) For detecting the recurrence of colorectal carcinoma

sensitivity

specificity and accuracy of 18FDG PET is 91.7%

100% and 98.3%

respectively; which of CT is 76.2%

61% and 75%

respectively. The sensitivity and accuracy of 18FDG PET in detecting the recurrence of colorectal carcinoma are significantly higher than those of CT. Thus 18FDG PET has superiority in detecting recurrence

local metastasis and qualitative analysis.

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18F-FDG PET显像在结直肠癌术后诊断中的临床应用

Clinical value of 18FDG PET in postoperative diagnosis of colorectal carcinoma

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¹⁸F-FDG PET显像在结直肠癌术后诊断中的临床应用

Clinical value of ¹⁸FDG PET in postoperative diagnosis of colorectal carcinoma