Synchrotron radiation X-ray fluorescence (SRXRF) micro-probe investigation of intracellular elements distribution in single smooth muscle cell with La(NO3)3
By using Synchrotron radiation X-ray fluorescence (SRXRF) micro-probe
the relative levels of intracellular important elements (such as K
Ca
Fe
Ni
Cu
Zn
La) in single smooth muscle cell of rat under the actions of 10 -8 mol/L La(NO 3) 3 within 4h
8h and 24h
were detected respectively. The changes of intracellular important elements distribution in single smooth muscle cell were observed. The accumulation of La 3+ in cell
causing the change of intracellular important elements distribution
is one of the mechanisms of biological effect of rare earth element (REE) in cells.