In order to investigate the adverse impact of hypertension SHR rats caused by simulated particle matter (nano ferric oxide) with radioactivity isotope tracer techniques was researched. By measured the radioactivity inten- sity in different tissues in different time point

we got the regular pattern of scavenging particles from pulmonary and the metabolism of the particles in a rat. The ultrafine particles can transport from the pulmonary to blood

then par- ticipated metabolism and expelled out of the body by feces in both hypertension rats and normal rats. The speed of unltrafine particulars transporting to blood is faster than the normal ones and expelled through feces in hypertension animals are less than those in normal rats. In conclusion

the ultrafine particles are more harmful to hypertension pa- tients because the particles can easily transport from lung to blood and be hardly scavenged from body through feces

so the hypertension patients may be the sensitive group by ultrafine particle in the atmosphere.