To investigate the relationship between bone element contents and bone mineral density (BMD)

left fe- mur of sham-operated rats (SHAM

n=5)

ovariectomized rats (OVX

n=5) and antler hemo-treated ovariectomized rats (OVX+ antler hemo

n=5) were analyzed by synchrotron radiation X-ray fluorescence (SRXRF) microprobe. The results showed that there were very good positive correlations among contents of Ca

P

Zn and Sr. In comparison to the SHAM group

decreased relative intensities of Ca

P

Zn and Sr (especially Ca and P

p<0.05) were observed in femur of the OVX group

which showed significant decrease (p<0.05) of the BMD. The results indicate that loss of Ca and P in bone will cause osteoporosis. On the other hand

increased relative intensities of Ca

P and Zn in femur

and the BMD (p<0.05)

of the anlter hemo-treated OVX group were found

in comparison to the OVX group. This suggests that anlter hemo may help cure osteoporosis through maintaining bone contents of Zn

Ca and P

and increasing the BMD.