YANG Mingjian1, 2 KONG Fuquan1 ZHAN Yong2 WANG Xiao1 NI Meinan1 SUI Li1 CAI Minghui1, 2 ZHAO Kui1, et al. A study of protective action of different scavengers on DNA damage induced by γ rays[J]. Nuclear techniques, 2007, (4): 255-258.
YANG Mingjian1, 2 KONG Fuquan1 ZHAN Yong2 WANG Xiao1 NI Meinan1 SUI Li1 CAI Minghui1, 2 ZHAO Kui1, et al. A study of protective action of different scavengers on DNA damage induced by γ rays[J]. Nuclear techniques, 2007, (4): 255-258.DOI:
To evaluate the effect of free radicals on DNA damage induced by heavy ions
pUC19 plasmid DNA solution with different kinds of scavengers(Mannitol
Vitamin C and Tea Polyphenols) is irradiated by γ rays. The DNA damages are analysed by gel electrophoresis and Alpha Innotech digital imaging system. The results show that all of the three kinds of scavengers can significantly protect DNA;mannitol is more effective than Vitamin C under the same condition;and their capacity of scavenging free radicals induced by γ rays is more remarkable than those induced by heavy ions.