To investigate the clinical features of complicated with pulmonary embolism nephrotic syndrome in children. 99m Tc-MAA pulmonary perfusion imaging was performed on 30 nephrotic syndrome in children with elevated plasma D-dimer. Results shown that 14 of 30 patients were found to have pulmonary embolism (46.7%). Pulmonary perfusion imaging showed an involvement of 1 pulmonary segment in 3 cases

2 segments in 2 cases and over 3 segments in other 9 cases. Among them

there were 7 segments involved in one case. After two weeks of heparin anticoagulative therapy

most cases showed a recovery. The result of this study suggested that pulmonary embolism is a common complication of nephrotic syndrome. Pulmonary perfusion imaging is simple

effective and accurate method for the diagnosis of pulmonary embolism

and it also can help to assess the value of clinical therapy.