To observe the influence of nifidipine(NIF) in 99mTc-MIBI myocardial tomography imaging. 35 patients with coronary artery disease were divided into NIF group and nitroglycerine(NTC) group. 48 hours after rest imaging

each patient was administrated NIF or NTC sublingually

then myocardial imaging was performed at 1 and 5 hours after injection of 99mTc-MIBI

these imagings were compared and analyzed. In NIF group

40.0% segments of low intake in rest imaging had improvement. But 33 segments at 1 hour imaging had lower intake than rest imaging

and 29 segments returned to normal at 5 hour. In NTC group

69.5% segments of low intake in rest imaging had improvement. It was not seen at 1 hour that segments had lower intake than rest imaging. 90mTc-MIBI NIF myocardial tomography imaging revealed some myocardial segments had transient low intake at 1 hour imaging

the exact explaination requires more studies.