DING Zigeng, YU Junfeng, YIN Duanzhi, et al. A Preliminary study on the labelling of immunoglobulin with 188Re[J]. Nuclear techniques, 2000, (11): 762-766.
DING Zigeng, YU Junfeng, YIN Duanzhi, et al. A Preliminary study on the labelling of immunoglobulin with 188Re[J]. Nuclear techniques, 2000, (11): 762-766.DOI:
SnCl2 reduction solution together with sodium gluconate was chosen to reduce Na188ReO4- and label human IgG. The labelling conditions were optimized. It was found that the labelling efficiency could reach 90% under the following condition: 1g/L protein with 5000 mole ratio AA in 2h reducing time at pH= 3
in mingled with 2.6×10-2- 8.0× 10-2mol/L SnCl2 in sodium gluconate and 188ReO4- at ambient temperature. The factors effecting labelling efficiency were studied and discussed.