SHEN Qinyan, HUANG Qun. The study on stability of formamidinesulfinic acid in methoxy isobutyl isonitrile for injection[J]. Nuclear techniques, 1999, (5): 263-267.
SHEN Qinyan, HUANG Qun. The study on stability of formamidinesulfinic acid in methoxy isobutyl isonitrile for injection[J]. Nuclear techniques, 1999, (5): 263-267.DOI:
In order to explore the optimal store condition and calculate the shelf life of methoxy isobutyl isonitrile (MIBI) for injection. The stability of formamidinesulfinic acid (FSA) in methoxy isobutyl isonitrile(MIBI) for injection was studied. FSA is determined by indirect iodometry analysis. The recovery was 98.0%-102.4%. Temperature and light are the major influence factors. Acceleration test showed that the degradation reaction was a first-order reaction. The activation energy E was 84.53kJ/mol. It was estimated that the shelf life of MIBI for injection kept in refrigerator might be longer than 13.7 months.