radio deficit area and threshold on the measurement of organ volumewere investigated using 3 groups of phantom. The results showed that the measuredvolume without attenuation correction was higher than the real volume of phantomsin the reconstruction of SPECT images. The measured volume was getting smaller asthe correction coefficient increased. When correction coefficient’ was 0.1
themeasured volume approximated mostly the real volume of phantom. There was nosignificant change in the measured volumed when radioactivity ranged from 37 to185kBq/mL (P>0.05). The measured volume decreased as threshold increasing andbest results were obtained when the threshold was 48%. The presence of radio deficitarea showed no influence for the determination of functional volume. Conclusions:the best results can be obtained with Change’s attenuation correction method inreconstruction with correction coefficient 0.1 and threshold 48%.