The study was performed with cold-induced ~99mTc (MIBI) myocardial imaging(MI) in 23 patients with systematic scleroderma. The left ventricular function andwall motion were also observed by dimensional echocardiography(UCG). 14 patientshad myocardial perfusion abnormalities visualized by MI

including 5 cases with fixeddefects of 9 segments

3 cases with reversible defects of 6 segments and 6 cases withboth fixed and reversible one of 14 segments. The positive rate in myocardial imaginghad no significant differences between patients with and without Raynaud’sphenomenon (0.5>P>0.25). Compared with baseline

the ejection fraction

strokevolume

cardiac output were significantly decreased during cold--induced in patientswith abnormal myocardial scinti-graphy (P<0.05)

and had significant differencecompared with normal group (P<0.05). 4 cases with cold-induced reversibleperfusion defects had anatomically correlated regional ventricular hypokinesis inUCG.