The addition of melamine into food caused serious social problems

hence the need of an easy way of detecting melamine and its derivatives.In this paper

we propose a new method based on the unique quenching effect of graphene oxide(GO).The difference of GO interaction with DNA and melamine is the basis of selective detection of melamine.GO adsorbs DNA and efficiently quenches the fluorescence of labeled fluorophores.The stronger interaction of melamine with GO than DNA leads to a competitive displacement of DNA out of the surface of GO

then a significant fluorescence increase appears.As a control

the glucose

maltose

and fructose do not cause significant fluorescence increase.This method is simple

inexpensive

sensitive and selective.It is suitable for rapid screening of large quantities of samples.