In this paper

we present a method for measurement and analysis of nuclear pulse signal

with which pile-up signal is removed

the signal baseline is restored

and the original signal is obtained.The data acquisition system includes FPGA

ADC and USB.The FPGA controls the high-speed ADC to sample the signal of nuclear radiation

and the USB makes the ADC work on the Slave FIFO mode to implement high-speed transmission status.Using the LabVIEW

it accomplishes online data processing of the blind deconvolution algorithm and data display.The simulation and experimental results demonstrate advantages of the method.