From September 2005 to November 2009

107 cases of keloids were treated by using 90Sr-90Y brachytherapy(25 Gy in 5 daily 5-Gy fractions

for 1–3 courses).No keloids were thicker than 6 mm.Questionnaires were developed to find assessment of the patients 12 months after the treatment.And χ2-test was used to tell the results differences according to the gender and recurrences.The radiation side effects were also recorded.The results showed that 65% patients considered the therapeutic outcome to be excellent or good

and 71% patients considered the cosmetic outcome to be excellent or good.Patients with keloids on ear or perineal were greatly satisfied with the outcome(both the therapeutic and cosmetic outcomes were 100%).The patients’ assessment had no significant difference in gender.And patients without recurrence enjoyed the relief from former keloid-caused symptoms compared to the patients with recurrence(P<0.05).The recurrence rate could be related to the keloid thickness(P<0.05).The recurrence did not have an influence on assessment in cosmetic outcome(P>0.05).The radiation side effects include telangiectasias(24%)

hyperpigmentation(43%) and depigmentation(33%)

but none of them was wild.No patients were found to get systemic adverse reactions.90Sr-90Y brachytherapy is a good method to treat patients with keloides of less than 6 mm in thickness.The therapeutic and cosmetic outcomes are acceptable

and 90Sr-90Y brachytherapy is a good choose for the patients who cannot tolerate the pain of operations or injections.