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1.第二军医大学长海医院
2.海军医学研究所
收稿日期:1985-03-08,
纸质出版日期:1986-09
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徐登仁, 陈四传, 潘文舟, 等. 133Хе吸入法测定局部脑血流量的临床应用[J]. 核技术, 1986,09(9):47-48,50,F3.
Dengren Xu, Sichuan Chen, Wenzhou Pan, et al. Clinical measurements of regional cerebral blood flow by 133Xe inhalation technique[J]. Nuclear techniques, 1986, 09(9): 47-48,50,F3.
局部脑血流量(rCBF)的测定对脑部疾病,特别是对缺血性脑血管病的诊断、病情估计、疗效观察及预后判断等都具有重要意义。
133
Xe吸入法测定rCBF具有无创伤性、安全、操作简便并可多次重复测定等优点。本法首先由Mallett及Veall提出,后经Obrist等诸多作者的研究与改进
[1-4]
,方法已日臻完善。我们在完成
133
Xe吸入测定rCBF方法学研究的基础上
[5]
,对临床有关疾病进行了观察,仅将初步结果报告如下。
rCBF was measured by
133
Xe inhalation technique in 106 normal adults
22 patients of functional headache and 22 patients of ischemic cerebral vascular disease. The total normal rCBF values (M±SD) were 63.2±7.7 ml/(min•100g) for the left and 63.4± 8.2 ml/(min•100g) for the right. The normal values of age over forty were 59.2± 6.3ml/(min•100g) for left and 60.2±7.1 ml/(min•100g)for right. The rCBF values of functional headache were 67.4±7.1 ml/(min•100g) for the left and 67.2±5.3 ml/(min•100g) for the right. In ischemic cerebral vascular disease the rCBF values were 45.6±9.2 ml/(min•100g) for the left and 47.0±8.4 ml/(min•100g) for the right. Acco rding to the level of rCBF the 22 patients of ischemic cerbral vascular disease were divided into three groups
and discussed. The ligusticum(Chuanxiong) can raise rCBF. The rCBF was raised significantly in 6 cases after giving ligusticum intramuscularly.
W. D, Obrist et al . , Stroke , 6 , 245 ( 1975 ).
J. Risberg et al . , ibid , 6 , 242 ( 1975 ).
J. S. Meyer et al . , ibid , 9 , 195 ( 1978 ).
J. B. Hazelrig et al . , IEEE Transactions on Biomedical Engineering , BME-28 , 609 ( 1981 ).
田伍训 等 , 中华核医学杂志 , 5 , 3 , 137 ( 1985 )。
田伍训 等 , 中华医学杂志 , 65 , 6 , 339 ( 1985 )。
V. A. Maximilian et al . , Stroke , 11 , 342 ( 1980 ).
北京制药工业研究所 , 中华医学杂志 , 57 , 467 ( 1977 )。
B. Norrving et al . , Stroke , 13 , 155 ( 1982 ).
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