Yaozhang Huang, Yongxin Wang, Xiaochun Wang, et al. Imaging of liver cancer in liver cancer bearing rats using anti-AFP monoclonal antibodies[J]. Nuclear techniques, 1989, 12(3): 185-188.
Yaozhang Huang, Yongxin Wang, Xiaochun Wang, et al. Imaging of liver cancer in liver cancer bearing rats using anti-AFP monoclonal antibodies[J]. Nuclear techniques, 1989, 12(3): 185-188.DOI:
I-labelled anti-AFP McAb IgG and normal mouse IgG were prepared and evaluated by radioimmunoimaging of a chemical induced liver cancer bearing rat and a human liver cancer xenografted nude mice. The imaging were made with a gamma camera at 24
48 and 72 h after intravenous injection of 3.7×10
6
Bq of
125
I-anti-AFP McAb containing lmg of IgG into each tumor-bearing animal. The accumulation of anti-AFP McAb in tumor was indicated but not with the same dose of
125
I-normal mouse IgG.
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