巴丹为一新型杀虫剂，对水稻螟虫、茶叶象甲、蔬菜和果树等的害虫具有高效、广谱和内吸的特性。其化学名称为1

3-双-（氨基甲酰硫基）-2-（N

N-二甲胺基）-丙烷盐酸盐，熔点183℃，溶于水，在酸性条件下很稳定，因而使用安全、方便，效果较好

[1]

。但是，对巴丹在进入机体内的吸收定位、排除途径和速度，以及是否有蓄积作用等毒性残留问题，至今未有阐明，我们在本研究中用液闪均相法及放射自显影探讨了

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S-巴丹在摄入体内时的一系列代谢动态过程。

Metabolism of

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S-patan was studied by means of macro-autoradiography and homogeneous liquid scintillation counting. The dynamic distribution of radioactivity in the body showed that this drug was absorbed rapidly and its accumulation decreasing with the order of kidney

liver duodenum

lung and trace in brain. This radioactive drug was eliminated rapidly with about 89.11% of the administered radioactivity in 48 hours after injection.

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S-patan was chiefly excreted in the urine and kept unchanged in form.