对从事放射性操作的人员来说，放射性钴是引起内照射污染的重要来源，尤其是在反应堆设备检修或更换反应堆内壳时，它是引起内照射污染的主要危害。它可以通过呼吸道和胃肠道摄入体内，危害操作人员的健康

[1]

。由于钴的可溶性化合物经胃肠道的吸收率可高达摄入量的30%左右

[2]

，所以对已进入接触人员胃肠道部位的放射性钴采取阻吸收措施和促排治疗是很有必要的。

This paper describes the laboratory animal studies on the prevention of absorption of

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Co from the gastrointestinal tract. The results suggest that sodium alginate is effective in reducing the absorption of

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Co from the gastrointestinal tract. In the first 2 days after giving radioactive cobalt by gastrolavage and administration of sodium alginate

the faecal excretion of

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Co was increased evidently while the elimination from the urine was decreased. In the meantine

the chelating agents 811 and DTPA were tested for the abilities of removing

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Co from the body. Both 811 and DTPA effectively promoted the quick excretion of radioactive cobalt from the urine. However the side-effect of 811 was smaller than DTPA hence the treatment of

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Co intoxication in the body by 811 is favourable.