Cyclotron production of gallium-67 citrate injection

Chen Sheng-yang; Zhang Liu-fang; Liu Jing-zhi; Cao Rong-zhen

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Cyclotron production of gallium-67 citrate injection

更新时间：2022-08-16

- Cyclotron production of gallium-67 citrate injection
- 回旋加速器制备放射性枸橼酸镓 (⁶⁷Ga) 注射液
- Nuclear Techniques 1980年03卷第3期
- 作者机构：
  
  Shanghai Institute of Nuclear Research, Chinese Academy of Sciences
- 作者简介：
- 基金信息：
- DOI：
  中图分类号：
- 收稿日期：1979-11-29，
  
  纸质出版日期：1980-06
- 稿件说明：
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Chen Sheng-yang, Zhang Liu-fang, Liu Jing-zhi, 等. Cyclotron production of gallium-67 citrate injection[J]. Nuclear Techniques, 1980,03(3):15-20.

声洋陈, 留芳张, 景芝刘, et al. 回旋加速器制备放射性枸橼酸镓 (⁶⁷Ga) 注射液[J]. 核技术, 1980, 03(3): 15-20.
Chen Sheng-yang, Zhang Liu-fang, Liu Jing-zhi, 等. Cyclotron production of gallium-67 citrate injection[J]. Nuclear Techniques, 1980,03(3):15-20. DOI：

声洋陈, 留芳张, 景芝刘, et al. 回旋加速器制备放射性枸橼酸镓 (⁶⁷Ga) 注射液[J]. 核技术, 1980, 03(3): 15-20. DOI：

摘要

Abstract

本文叙述了在1.2米回旋加速器的外靶上，用26.8MeV的α粒子束和13.4MeV的

粒子束，分别轰击天然铜靶和天然锌靶，制备无载体

Ga的方法。其厚靶产额分别为165µCi/µAh和350 µCi/µAh。无载体

Ga的化学分离采用异丙醚溶剂萃取法。枸橼酸镓（

Ga）注射液的制备采用3~3.8%枸橼酸钠溶液浸取。整个工艺流程需时4小时，操作简便，安全可靠，其化学产率可达90%以上。

The production of carrier-free gallium-67 at external target of the 1.2M cyclotron is described. It was produced by bombardment of natural copper with 26.8 MeV

and natural zinc with 13.4 MeV deuterium

gave thick-target yields of 165μCi/μAh and 350µCi/μAh

respectively. Radiochemical separation of carrier-free gallium-67 from target was carried out by isopropyl ether extraction. Gallium-67 citrate injection was prepared by sodium citrate leaching. The overall chemical procedure took 4 hours and the operations were simple and safe. The chemical yield was greater than 90%.

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references

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