Optimized focusing plan for short X-ray wavelengths mode at BL17U in SSRF

Changyou ZHONG; Qisheng WANG; Ke LIU; Kunhao ZHANG; Jianhua HE

doi:10.11889/j.0253-3219.2018.hjs.41.050102

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Optimized focusing plan for short X-ray wavelengths mode at BL17U in SSRF

SYNCHROTRON RADIATION TECHNOLOGY AND APPLICATIONS | 更新时间：2021-05-19

- Optimized focusing plan for short X-ray wavelengths mode at BL17U in SSRF
- NUCLEAR TECHNIQUES Vol. 41, Issue 5, Article number: 050102(2018)
- 作者机构：
  
  1.中国科学院上海应用物理研究所张江园区上海 201204
  2.中国科学院大学北京 100049
- 作者简介：
- 基金信息：
  
  Youth Innovation Promotion Association of Chinese Academy of Sciences;National Natural Science Foundation of China
- DOI：10.11889/j.0253-3219.2018.hjs.41.050102
  CLC： TL99
- Received：04 December 2017，
  
  Revised：30 January 2018，
  
  Published：10 May 2018
- 稿件说明：
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Changyou ZHONG, Qisheng WANG, Ke LIU, et al. Optimized focusing plan for short X-ray wavelengths mode at BL17U in SSRF[J]. Nuclear techniques, 2018, 41(5): 050102
DOI：

Changyou ZHONG, Qisheng WANG, Ke LIU, et al. Optimized focusing plan for short X-ray wavelengths mode at BL17U in SSRF[J]. Nuclear techniques, 2018, 41(5): 050102 DOI： 10.11889/j.0253-3219.2018.hjs.41.050102.

摘要

蛋白质数据库中超过80%的蛋白质都是用X射线衍射解出的结构，其中最常用的波长是0.0972 nm。有研究表明短波长X射线可以减少晶体的辐射损伤，提高X射线衍射数据的质量，为了在上海同步辐射光源生物大分子线站BL17U上进一步研究短波长X射线测定蛋白质结构，需要先对其能区进行拓展。基于复合折射透镜（Compound Refractive Lens，CRL）聚焦X射线的原理，讨论了在BL17U上用其聚焦短波长X射线的可行性。通过引入接受率

这一物理量计算了单一结构不同曲率半径的CRL聚焦光子后的通量和通量密度，同时也计算了级联式紧密接触型CRL和级联式相间型CRL两种方式的聚焦的效果。在充分考虑聚焦效果、实验站布局等因素，提出在BL17U聚焦短波长X射线的最佳方案，用31片半径50 μm的透镜理论上可以将25keV的光子聚焦，得到的通量密度3.2018×10

-1

·mm

-2

。通过这些理论计算可以为BL17U研究短波长X射线测定蛋白质结构做前期准备。

Abstract

Background

More than 80% of the protein in the protein database is solved by X-ray diffraction. The most commonly used wavelength is 0.0972 nm. Studies have shown that short-wavelength X-rays can reduce the radiation damage of crystals and improve the quality of X-ray diffraction data.

Purpose

In order to collect X-ray diffraction data from protein crystals with shorter wavelength at beamline BL17U in Shanghai Synchrotron Radiation Facility (SSRF)

our first priority is to extend its energy range to 25 keV using compound refractive lens (CRL).

Methods

The flux rate and flux density of the CRL focused photon with different curvature radius of a single structure are calculated by introducing the acceptance rate

. The close contact type CRL and the interphase type CRL are also calculated.

Results

Focusing on the factors such as the focusing effect and the layout of the experimental station

we propose the best solution for focusing short-wavelength X-rays in BL17U. Using 31 lenses with a radius of 50 μm can obtain 3.2018×10

-1

·mm

-2

at 25 keV theoretically.

Conclusion

Through these theoretical calculation

we can prepare for collect protein crystal data using short X-ray wavelengths in BL17U.

关键词

Keywords

references

C K Djinovic , J R Helliwell , H Stuhrmann , . Softer and soft X-rays in macromolecular crystallography . Journal Synchrotron Radiation , 2005 . 12 ( Pt4 ): 410 - 419 . DOI: 10.1107/S0909049504025762 http://doi.org/10.1107/S0909049504025762 .

M S Lehmann , H H Müller , H B Stuhrmann . Protein single-crystal diffraction with 5 A synchrotron X-rays at the sulfur K-absorption edge . Acta Crystallographica , 1993 . 49 ( Pt2 ): 308310 DOI: 10.1107/S0907444992011910 http://doi.org/10.1107/S0907444992011910 .

A Gonzalez , R Denny , C Nave . Data collection at short wavelengths in protein crystallography . Acta Crystallographica , 1994 . 50 ( 3 ): 276 - 282 . DOI: 10.1107/S0907444993013101 http://doi.org/10.1107/S0907444993013101 .

J Jakoncic , M D Michiel , Z Zhong , . Anomalous diffraction at ultra-high energy for protein crystallography . Journal of Applied Crystallography , 2006 . 39 ( 6 ): 831 - 841 . DOI: 10.1107/s0021889806036387 http://doi.org/10.1107/s0021889806036387 .

M Schiltz , Å Kvick , O S Svensson , . Protein crystallography at ultra-short wavelengths:feasibility study of anomalous-dispersion experiments at the xenon K-edge . Journal of Synchrotron Radiation , 1997 . 4 ( 5 ): 287 - 297 . DOI: 10.1107/S0909049597008571 http://doi.org/10.1107/S0909049597008571 .

李昌亮, 田顺强, 张文志. 上海光源二期工程的垂直发射度研究[J]. 核技术, 2016, 39(5): 050102. DOI: 10.11889/j.0253-3219.2016.hjs.39.050102. http://dx.doi.org/10.11889/j.0253-3219.2016.hjs.39.050102.

LI Changliang, TIAN Shunqiang, ZHANG Wenzhi. Study on the vertical emittance for the SSRF Phase Ⅱ project[J]. 2016, 39(5): 050102. DOI: 10.11889/j.0253-3219.2016.hjs.39.050102. http://dx.doi.org/10.11889/j.0253-3219.2016.hjs.39.050102.

Q S Wang , F Yu , S Huang , . The macromolecular crystallography beamline of SSRF . Nuclear Science and Techniques , 2015 . 26 ( 1 ): 010102 DOI: 10.13538/j.1001-8042/nst.26.010102 http://doi.org/10.13538/j.1001-8042/nst.26.010102 .

A Snigirev , V Kohn , I Snigireva , . A compound refractive lens for focusing high-energy X-rays . Applied Optics , 1996 . 37 ( 4 ): 4951 DOI: 10.1038/384049a0 http://doi.org/10.1038/384049a0 .

A Snigirev , V Kohn , I Snigireva , . Focusing high-energy X rays by compound refractive lenses . Applied Optics , 1998 . 37 ( 4 ): 653 DOI: 10.1364/ao.37.000653 http://doi.org/10.1364/ao.37.000653 .

B Lengeler , J Tümmler , A Snigirev , . Transmission and gain of singly and doubly focusing refractive X-ray lenses . Journal of Applied Physics , 1998 . 84 ( 11 ): 58555861 DOI: 10.1063/1.368899 http://doi.org/10.1063/1.368899 .

B Lengeler , C G Schroer , B Benner , . Parabolic refractive X-ray lenses:a breakthrough in X-ray optics . Nuclear Instruments & Methods in Physics Research A , 2001 . 467 ( 2002 ): 944 - 950 . DOI: 10.1016/s0168-9002(01)00531-9 http://doi.org/10.1016/s0168-9002(01)00531-9 .

J W Goodman , E Huggins . Introduction to Fourier optics , 2nd ed Optical Engineering , 1995 . 75 - 78 . DOI: 10.1117/1.601121 http://doi.org/10.1117/1.601121 .

B Lengeler , C Schroer , J Tümmler , . Imaging by parabolic refractive lenses in the hard X-ray range . Journal of Synchrotron Radiation , 1999 . 6 ( 6 ): 1153 - 1167 . DOI: 10.1107/S0909049599009747 http://doi.org/10.1107/S0909049599009747 .

付明磊 , 乐孜纯 , 周寒青 , . 级联式平面抛物面型X射线组合折射透镜的设计与制作 . 物理学报 , 2014 . 63 ( 19 ): 194103 DOI: 10.3788/OPE.20152313.0000 http://doi.org/10.3788/OPE.20152313.0000 .

Minglei FU , Zichun LE , Hanqing ZHOU , . Design and fabrication of cascaded X-ray planar parabolic compound refractive lens . Acta Physica Sinica , 2014 . 63 ( 19 ): 194103 DOI: 10.3788/OPE.20152313.0000 http://doi.org/10.3788/OPE.20152313.0000 .

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