ZHANG Wenyi, LIU Zhongchao, RUAN Shuzhou, et al. Radial and axial dose distribution of I-125 seed brachytherapy[J]. Nuclear techniques, 2014, 37(4): 040202
DOI:
ZHANG Wenyi, LIU Zhongchao, RUAN Shuzhou, et al. Radial and axial dose distribution of I-125 seed brachytherapy[J]. Nuclear techniques, 2014, 37(4): 040202 DOI: 10.11889/j.0253-3219.2014.hjs.37.040202.
Radial and axial dose distribution of I-125 seed brachytherapy
Background: Iodine-125 seeds brachytherapy is a cancer treatment method with seeds implanted in tumor tissue. Before clinic application
experiments should be done to determine the dosimetric parameters of seed due to their influences on treatment effects. In this paper
using thermoluminescent dosimeters (TLD) method
axial and radial dose distribution of Iodine-125 seed are measured and analyzed in the lumen tissue model. Purpose: The aim is to investigate the radial and axial dosimetric properties of I-125 seed
and provide scientific data for cavity cancers treatments with seeds brachtherapy. Methods: LiF (Mg
Cu
P) TL flake
grain and glass dosimeters were used for analog measurements of dose distribution inside the cavity phantom. Three kinds of TLD were measured by FJ-427A1 spectrometer after irradiation. Results: The radial dose distribution at different directions was anisotropic
and the variance of axial dose distribution was more than 10%. These results indicated that the iodide rod inside the titanium tube might deviate from the center of the axial. Conclusion: It is necessary to study the influences of seeds dosimetric parameters and arrangements on possible brachytherapy effects.Cited