Preparation of [4,4-<sup>3</sup>H]-γ-amino butyric acid

Dong Mo Cao Rongzhcn

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Preparation of [4,4-³H]-γ-amino butyric acid

更新时间：2021-04-20

- Preparation of [4,4-³H]-γ-amino butyric acid
- NUCLEAR TECHNIQUES Issue 6, (1991)
- 作者机构：
  
  中国科学院上海原子核研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：01 June 1991
- 稿件说明：
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[1]董墨,曹蓉珍.高比度[4,4-~3H]-γ-氨基丁酸的制备[J].核技术,1991(06):372-374.

Dong Mo Cao Rongzhcn. Preparation of [4,4-³H]-γ-amino butyric acid[J]. Nuclear techniques, 1991, (6): 372-374.
[1]董墨,曹蓉珍.高比度[4,4-~3H]-γ-氨基丁酸的制备[J].核技术,1991(06):372-374. DOI：

Dong Mo Cao Rongzhcn. Preparation of [4,4-³H]-γ-amino butyric acid[J]. Nuclear techniques, 1991, (6): 372-374. DOI：

摘要

本文报道高比活度氚标记γ-氨基丁酸的合成。[4

H]-γ-氨基丁酸是由β-氰基丙酸在乙醇溶液中催化氚化制得。β-氰基丙酸是通过用氯胺-T对谷氨酸氧化而得。产品的比度是1.51TBq/mmol

放化纯度大于95％。

Abstract

4-3H]-γ-amino butyric acid was fcrmed from theβ-cyano propionic acid by catalytic reduction in ethanol medium

using tritium gas. β-cyano propionic acid was prepared from glutamic acid by oxidization with chloramine-T. The specific activity of product was 1.51TBq/ mmol

while the radiochemical purity was over 95% by paper chromatography.

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Preparation of [4,4-3H]-γ-amino butyric acid

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摘要

Abstract

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Preparation of [4,4-³H]-γ-amino butyric acid