Uptake and release of <sup>99m</sup>Tc-CPI in cultured myocardial cells

Li Shengting Xiao Yanling Yu Qifu Zhang Hongyuan

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Uptake and release of ^99mTc-CPI in cultured myocardial cells

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- Uptake and release of ^99mTc-CPI in cultured myocardial cells
- NUCLEAR TECHNIQUES Issue 11, (1991)
- 作者机构：
  
  1. 白求恩医科大学三院
  2. 山东潍坊医学院
- 作者简介：
- 基金信息：
- DOI：
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- Published：01 November 1991
- 稿件说明：
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[1]李胜亭,孝延龄,于起福,张鸿源,唐景荣.~(99m)Tc-CPI在培养乳鼠心肌细胞的浓聚与清除[J].核技术,1991(11):647-649.

Li Shengting Xiao Yanling Yu Qifu Zhang Hongyuan. Uptake and release of ^99mTc-CPI in cultured myocardial cells[J]. Nuclear techniques, 1991, (11): 647-649.
[1]李胜亭,孝延龄,于起福,张鸿源,唐景荣.~(99m)Tc-CPI在培养乳鼠心肌细胞的浓聚与清除[J].核技术,1991(11):647-649. DOI：

Li Shengting Xiao Yanling Yu Qifu Zhang Hongyuan. Uptake and release of ^99mTc-CPI in cultured myocardial cells[J]. Nuclear techniques, 1991, (11): 647-649. DOI：

摘要

本文研究了在正常条件下（37℃

pH7.4）培养乳鼠心肌细胞中

Tc-CPI的浓聚和清除。在与37kBq

99m

Tc-CPI孵育41.1min时心肌细胞的浓聚达坪值（4291.6cpm/mg cell protein）。其清除分为两个部分:快相半排时间为3.3min;慢相半排时间为198.0min。说明

99m

Tc-CPI在心肌细胞中的浓聚与被动扩散有关。

Abstract

The uptake and release of 99mTc-CPI were studied in cultured monolayer neonatal rat myocardial cells incubated under normal condition （37℃

pH 7.4）. The plateau level of uptake （4291.6 cpm/mg cell protein） was reached at 41.1 min when incubated with 37 kBq 99mTc-CPI. The 99mTc-CPI release was composed of at least two components. The fast component had a half-time （t1/2） of 3.3min and the slow one had a t1/2 of 198.0 min. It was suggested by the authors that the uptake of 99mTc-CPI by cultured myocardial cells might be related to passive difussion.

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Uptake and release of 99mTc-CPI in cultured myocardial cells

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摘要

Abstract

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Uptake and release of ^99mTc-CPI in cultured myocardial cells