Comparison of 99mTc-sestamibi SPECT and 18F-FDG PET imaging in the diagnosis of recurrence and malignancy of glioma[J]. Nuclear techniques, 1998, (5): 271-274.
Comparison of 99mTc-sestamibi SPECT and 18F-FDG PET imaging in the diagnosis of recurrence and malignancy of glioma[J]. Nuclear techniques, 1998, (5): 271-274.DOI:
Comparison of 99mTc-sestamibi SPECT and 18F-FDG PET imaging in the diagnosis of recurrence and malignancy of glioma
This study compares the diagnostic value of 18F-FDG PET and 99mTc-MIBISPECT imaging in the diagnosis of recurrence and malignancy of glioma. 28 patientswith glioma post treatment were performed by MRI or/and CT and 18F-FDG PETimagmg
and 14 of them were also performed by 99mTc-MIBI SPECT. On PET scans
10 patients were hypometabolic
4 patients were central non-metabolic withperipheral rm FDG uptake
14 patients were hypermetabolic. Out of 8 patients withastrocytoma Ⅰ - Ⅱ grade confirmed by operation
5 ones showed hypermetabolic
indicating malignant degeneration of low-grade glioma. The sensitivity and accuracyof 18F-FDG PET and 99mTc-MIBI SPECT in the diagnosis of recurrence andmalignant degeneration of glioma were 93.3%
94.1% and 91.7%
85.7% respectively.FDG PET imaging is the most accurate method in the detection of recurrence andmalignant degeneration of low-grade glioma
compared with MRI enhancement and99mTc-MIBI SPECT. The extent of lesion site detected by MIBI scans is usuallybigger than FDG PET imaging.