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中国科学院近代物理研究所
Published:01 April 1997
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[1]颉红梅,卫增泉,李文建,周光明,陈卫强,黄涛.重离子束均匀度的测定及治癌束流成形的模拟试验[J].核技术,1997(04):39-43.
Xie Hongmei Wei Zengquan Li Wenjian Zhou Guangming Chen Weiqiang Huang Tao. Determination of homogeneity of heavy ion beam and a simulation test of beam shaping for cancer therapy[J]. Nuclear techniques, 1997, (4).
采用50μm厚聚碳酸酯薄膜、利用核径迹探测技术测得φ40mm的25MeV/u40;Ar14;离子束的均匀度在散焦情况下为32.7%,在“散焦+样品旋转”情况下为52.4%。还采用多层聚碳酸酯薄膜组件作为肿瘤块等效材料,进行了重离子束治癌束流成形模拟试验,通过对25MeV/u40;Ar14;离子束9个间隔的降能来移动其Bragg峰位,并在各个峰位上经过光阑赋予不同的束流截面,由不同层面上的截面可以构成一肿瘤块的椭球状。利用这种方法辐照聚碳酸酯薄膜组件,经化学蚀刻处理后,利用离子径迹小孔对普通光柱的透射与衍射,得到了类似于椭球形肿瘤的光球,光球范围就反映了重离子束能损集中的Bragg峰作用的部位。
The homogeneity of 25MeV/u 40 Ar 14 ion beam (40mm) was measured with 50μm polycarbonate films by means of nuclear track detection. It was 32.7% for the case of defocus and 52.4% for “defocus+sample rotation”. A simulation test of beam shaping for heavy-ion cancer therapy was carried out with an assembly of multilayer polycarbonate films as the tumour equivalent material. The Bragg-peak was moved at nine locations through energy degradation of the heavy ions. The beam cross sections at each Bragg-peak location were defined by different apertures. Thus
an ellipsoid like tumour was formed from the cross-sections of different layers. A light-ball similar to the ellipsoid tumour was obtained by means of transmission and diffraction of a light column passing through ion track pores in the irradiated polycarbonate films after chemical etching. The sphere of the light-ball corresponded to the space effected by Bragg-peaks where the energy loss of heavy ions was concentrated.
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