Thyroid cold nodules in 56 patients found in 99m TcO 4 - imaging （37 in malignant

19 in benign as proved by pathology）

were performed 99m Tc-MIBI imaging. The results showed that all of 22 cases （22/56） were rich in blood flow

among them 20 cases （20/37） in malignant group

and 2 cases （2/19） in benign group. There were very significant difference （P<0.001） between T/NT in 99m Tc-MIBI and 99m TcO 4 - imaging in papilary

folicular

medullary and anaplastic cancers of malignant group

and significant difference （P<0.05） in adenomas of benign group. The positive rate

accuracy and sensitivity of 99m Tc-MIBI imaging was 75.8%

78.6% and 84.2% respectively. Thereby

it may have some help for the differentiation of the property of thyroid cold nodule in clinical practice.