Preparation and basic study of         99m  42;Tc-Diol, a renal imaging agent

Liu Jinman   He Qun   Li Pengfei

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Preparation and basic study of 99m 42;Tc-Diol, a renal imaging agent

更新时间：2021-04-09

- Preparation and basic study of 99m 42;Tc-Diol, a renal imaging agent
- NUCLEAR TECHNIQUES Issue 5, (1997)
- 作者机构：
  
  中国医科大学
- 作者简介：
- 基金信息：
- DOI：
  CLC： R692
- Published：01 May 1997
- 稿件说明：
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[1]刘金满,何群,李鹏飞.肾显像剂 ~(99m)Tc-Diol 的制备及其基础实验[J].核技术,1997(05):26-28.

Liu Jinman He Qun Li Pengfei. Preparation and basic study of 99m 42;Tc-Diol, a renal imaging agent[J]. Nuclear techniques, 1997, (5).
[1]刘金满,何群,李鹏飞.肾显像剂 ~(99m)Tc-Diol 的制备及其基础实验[J].核技术,1997(05):26-28. DOI：

Liu Jinman He Qun Li Pengfei. Preparation and basic study of 99m 42;Tc-Diol, a renal imaging agent[J]. Nuclear techniques, 1997, (5). DOI：

摘要

报道了肾显像剂９９ｍＴｃ－１，２－二羟基丙基磷酸（Ｄｉｏｌ）的制备方法及其动物实验研究。结果显示，９９ｍＴｃ－Ｄｉｏｌ注入小鼠体内５ｍｉｎ后在肾脏达最大摄取率（３４．０６±４．６７％ＩＤ／ｇ）；注入家兔５ｍｉｎ后双肾动态显像最清晰。表明９９ｍＴｃ－Ｄｉｏｌ是一种肾脏摄取率高、摄取速度快的新型肾显像剂。

Abstract

The present work concerns the preparation of 99m Tc-1

2-dihydroxy-propyl-1-phosphonic acid （ 99m Tc-Diol）

and the biodistribution studies in mice. Renal scintigraphy by rabbit showed that 99m Tc-Diol has specific affinity for the kidneys.

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