125  I radioiodination of BMIPP and its distribution in animals

Zhong Gaoren   Chen Shaoliang   Xu Lanwen   Xiu Yan  Sun Xiaoguang   Chen Kejing   Zhao Huiyang   Zhu Tong

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125 I radioiodination of BMIPP and its distribution in animals

更新时间：2021-04-09

- 125 I radioiodination of BMIPP and its distribution in animals
- NUCLEAR TECHNIQUES Issue 5, (1997)
- 作者机构：
  
  上海医科大学
- 作者简介：
- 基金信息：
- DOI：
  CLC： R542.2
- Published：01 May 1997
- 稿件说明：
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[1]钟高仁,陈绍亮,许兰文,修雁,孙晓光,陈可靖,赵惠扬,朱桐.侧链脂肪酸 BMIPP 的 ~(125)I 标记和动物体内分布[J].核技术,1997(05):22-25.

Zhong Gaoren Chen Shaoliang Xu Lanwen Xiu Yan Sun Xiaoguang Chen Kejing Zhao Huiyang Zhu Tong. 125 I radioiodination of BMIPP and its distribution in animals[J]. Nuclear techniques, 1997, (5).
[1]钟高仁,陈绍亮,许兰文,修雁,孙晓光,陈可靖,赵惠扬,朱桐.侧链脂肪酸 BMIPP 的 ~(125)I 标记和动物体内分布[J].核技术,1997(05):22-25. DOI：

Zhong Gaoren Chen Shaoliang Xu Lanwen Xiu Yan Sun Xiaoguang Chen Kejing Zhao Huiyang Zhu Tong. 125 I radioiodination of BMIPP and its distribution in animals[J]. Nuclear techniques, 1997, (5). DOI：

摘要

在乙醇和水的混合溶液中，通过新生态Ｃｕ（Ｉ）催化碘同位素交换反应制得１２５Ｉ－ＢＭＩＰＰ，经乙醚提取纯化后，其放射化学纯度＞９５％，制备过程中总放射性得率＞４０％。小白鼠体内分布显示２％左右的注射剂量存在于心肌组织，且长时间保持稳定。

Abstract

I-BMIPP was prepared by isotopic exchange using Cu（Ⅰ） as catalyst in an ethanal water mixture. The radiochemical purity of 125 I-BMIPP was >95%

and the overall radioactivity yield was >40%. In rat

the myocardum kept about 2% of injection dose and stabilized in 3 h. It indicated that BMIPP is a suitable agent for myocardial fatty acid metabolism imaging.

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¹²³I标记侧链脂肪酸BMIPP的研制

The structural modification and nuclide labelling of avidin

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中国科学院上海原子核研究所

复旦大学医学院实验动物学部

Shanghai Institute of Nuclear Research, the Chinese Academy of Sciences

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