fter temporary occlusion of left hepatic vein

hepatic arterial embolization （HAE） were performed with 131 I-lipiodol

it can improve the effectiveness of HAE in treatment of hepatocillular carcinoma Using the pig as a model

during the course of embolization of the left hepatic artery with 131I-lipiodol

temporary occlusion of the left hepatic vein was done in the experimental group Lipiodol was labelled with 131I using exchanged reaction method The labelled rate was 95% The lung/liver radioactive ratio

radioactive distribution and the condition of radioactive decay in body was obtained by the SPECT imaging after operation The radioactive ratio of the lung/liver in experimental group was lower than that in control group （<005） on the 1st and 3rd days after operation and has no significant difference on the 5th

7th and 14th days （<005） The effective half-life of 131I-lipiodol was 453 day （median） The pathological change of experimental group was more severe than control group expressing spotty infarct

fibrinoid necrosis

coagulation necrosis etc The result of experiment showed that this method is safe

effective and can tentatively be used clinically