A new method of indirect labelling monoclonal antibodies with 99m  Tc

Zhang Kaijun   An Rui   Zhang Yongxue   Ye Weixin   Gao Zairong

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A new method of indirect labelling monoclonal antibodies with 99m Tc

更新时间：2021-04-09

- A new method of indirect labelling monoclonal antibodies with 99m Tc
- NUCLEAR TECHNIQUES Issue 11, (1997)
- 作者机构：
  
  1. 同济医科大学附属协和医院
  2. 同济医科大学实验中心
  3. 同济医科大学附属协和医院同济医科大学实验中心
- 作者简介：
- 基金信息：
- DOI：
  CLC： TL923
- Published：01 November 1997
- 稿件说明：
移动端阅览
[1]张凯军,安锐,张永学,叶维新,高再荣.~(99m)Tc 间接标记单克隆抗体的方法[J].核技术,1997(11):47-50.

Zhang Kaijun An Rui Zhang Yongxue Ye Weixin Gao Zairong. A new method of indirect labelling monoclonal antibodies with 99m Tc[J]. Nuclear techniques, 1997, (11).
[1]张凯军,安锐,张永学,叶维新,高再荣.~(99m)Tc 间接标记单克隆抗体的方法[J].核技术,1997(11):47-50. DOI：

Zhang Kaijun An Rui Zhang Yongxue Ye Weixin Gao Zairong. A new method of indirect labelling monoclonal antibodies with 99m Tc[J]. Nuclear techniques, 1997, (11). DOI：

摘要

研究了用９９ｍＴｃ间接标记抗体的方法，讨论了各种因素对标记率的影响。结果表明，应用此法标记物稳定，其标记率在９５％以上。经兔炎症模型、犬血栓模型及免疫病理检测证明标记后的抗体保持了良好的活性。

Abstract

? A method for labelling antibodies （poly or monoclonal） indirectly with 99m Tc is studied The various factors that effect the labelling yield are discussed The result shows that labelling yields are more than 95% Imaging of rabbit inflammatory model

dog thrombus model and test of immune pathology show that the labelling antibody has good bioactivity

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